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Page 1
A multi-center study of ACE and the risk of late-onset Alzheimer's disease.
Belbin O, Brown K, Shi H, Medway C, Abraham R, Passmore P, Mann D, Smith AD, Holmes C, McGuinness B, Craig D, Warden D, Heun R, Kölsch H, Love S, Kalsheker N, Williams J, Owen MJ, Carrasquillo M, Younkin S, Morgan K, Kehoe PG. Belbin O, et al. Among authors: brown k. J Alzheimers Dis. 2011;24(3):587-97. doi: 10.3233/JAD-2011-101914. J Alzheimers Dis. 2011. PMID: 21297258 Free PMC article.
Investigating statistical epistasis in complex disorders.
Turton JC, Bullock J, Medway C, Shi H, Brown K, Belbin O, Kalsheker N, Carrasquillo MM, Dickson DW, Graff-Radford NR, Petersen RC, Younkin SG, Morgan K. Turton JC, et al. Among authors: brown k. J Alzheimers Dis. 2011;25(4):635-44. doi: 10.3233/JAD-2011-110197. J Alzheimers Dis. 2011. PMID: 21483092
Genetic variants influencing human aging from late-onset Alzheimer's disease (LOAD) genome-wide association studies (GWAS).
Shi H, Belbin O, Medway C, Brown K, Kalsheker N, Carrasquillo M, Proitsi P, Powell J, Lovestone S, Goate A, Younkin S, Passmore P; Genetic and Environmental Risk for Alzheimer's Disease Consortium; Morgan K; Alzheimer's Research UK Consortium. Shi H, et al. Among authors: brown k. Neurobiol Aging. 2012 Aug;33(8):1849.e5-18. doi: 10.1016/j.neurobiolaging.2012.02.014. Epub 2012 Mar 23. Neurobiol Aging. 2012. PMID: 22445811 Free PMC article.
The role of ECE1 variants in cognitive ability in old age and Alzheimer's disease risk.
Hamilton G, Harris SE, Davies G, Liewald DC, Tenesa A, Payton A, Horan MA, Ollier WE, Pendleton N; Genetic and Environmental Risk for Alzheimer's Disease (GERAD1) Consortium; Starr JM, Porteous D, Deary IJ. Hamilton G, et al. Am J Med Genet B Neuropsychiatr Genet. 2012 Sep;159B(6):696-709. doi: 10.1002/ajmg.b.32073. Epub 2012 Jun 12. Am J Med Genet B Neuropsychiatr Genet. 2012. PMID: 22693153
Discovery by the Epistasis Project of an epistatic interaction between the GSTM3 gene and the HHEX/IDE/KIF11 locus in the risk of Alzheimer's disease.
Bullock JM, Medway C, Cortina-Borja M, Turton JC, Prince JA, Ibrahim-Verbaas CA, Schuur M, Breteler MM, van Duijn CM, Kehoe PG, Barber R, Coto E, Alvarez V, Deloukas P, Hammond N, Combarros O, Mateo I, Warden DR, Lehmann MG, Belbin O, Brown K, Wilcock GK, Heun R, Kölsch H, Smith AD, Lehmann DJ, Morgan K. Bullock JM, et al. Among authors: brown k. Neurobiol Aging. 2013 Apr;34(4):1309.e1-7. doi: 10.1016/j.neurobiolaging.2012.08.010. Epub 2012 Oct 1. Neurobiol Aging. 2013. PMID: 23036584 Free article.
The sex-specific associations of the aromatase gene with Alzheimer's disease and its interaction with IL10 in the Epistasis Project.
Medway C, Combarros O, Cortina-Borja M, Butler HT, Ibrahim-Verbaas CA, de Bruijn RF, Koudstaal PJ, van Duijn CM, Ikram MA, Mateo I, Sánchez-Juan P, Lehmann MG, Heun R, Kölsch H, Deloukas P, Hammond N, Coto E, Alvarez V, Kehoe PG, Barber R, Wilcock GK, Brown K, Belbin O, Warden DR, Smith AD, Morgan K, Lehmann DJ. Medway C, et al. Among authors: brown k. Eur J Hum Genet. 2014 Feb;22(2):216-20. doi: 10.1038/ejhg.2013.116. Epub 2013 Jun 5. Eur J Hum Genet. 2014. PMID: 23736221 Free PMC article.
Replication by the Epistasis Project of the interaction between the genes for IL-6 and IL-10 in the risk of Alzheimer's disease.
Combarros O, van Duijn CM, Hammond N, Belbin O, Arias-Vásquez A, Cortina-Borja M, Lehmann MG, Aulchenko YS, Schuur M, Kölsch H, Heun R, Wilcock GK, Brown K, Kehoe PG, Harrison R, Coto E, Alvarez V, Deloukas P, Mateo I, Gwilliam R, Morgan K, Warden DR, Smith AD, Lehmann DJ. Combarros O, et al. Among authors: brown k. J Neuroinflammation. 2009 Aug 23;6:22. doi: 10.1186/1742-2094-6-22. J Neuroinflammation. 2009. PMID: 19698145 Free PMC article.
Concordant association of insulin degrading enzyme gene (IDE) variants with IDE mRNA, Abeta, and Alzheimer's disease.
Carrasquillo MM, Belbin O, Zou F, Allen M, Ertekin-Taner N, Ansari M, Wilcox SL, Kashino MR, Ma L, Younkin LH, Younkin SG, Younkin CS, Dincman TA, Howard ME, Howell CC, Stanton CM, Watson CM, Crump M, Vitart V, Hayward C, Hastie ND, Rudan I, Campbell H, Polasek O, Brown K, Passmore P, Craig D, McGuinness B, Todd S, Kehoe PG, Mann DM, Smith AD, Beaumont H, Warden D, Holmes C, Heun R, Kölsch H, Kalsheker N, Pankratz VS, Dickson DW, Graff-Radford NR, Petersen RC, Wright AF, Younkin SG, Morgan K. Carrasquillo MM, et al. Among authors: brown k. PLoS One. 2010 Jan 19;5(1):e8764. doi: 10.1371/journal.pone.0008764. PLoS One. 2010. PMID: 20098734 Free PMC article.
8,643 results