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Cationic host defense (antimicrobial) peptides.
Brown KL, Hancock RE. Brown KL, et al. Curr Opin Immunol. 2006 Feb;18(1):24-30. doi: 10.1016/j.coi.2005.11.004. Epub 2005 Dec 6. Curr Opin Immunol. 2006. PMID: 16337365 Review.
Bovine and human cathelicidin cationic host defense peptides similarly suppress transcriptional responses to bacterial lipopolysaccharide.
Mookherjee N, Wilson HL, Doria S, Popowych Y, Falsafi R, Yu JJ, Li Y, Veatch S, Roche FM, Brown KL, Brinkman FS, Hokamp K, Potter A, Babiuk LA, Griebel PJ, Hancock RE. Mookherjee N, et al. Among authors: brown kl. J Leukoc Biol. 2006 Dec;80(6):1563-74. doi: 10.1189/jlb.0106048. Epub 2006 Aug 30. J Leukoc Biol. 2006. PMID: 16943385
IRAK-4 mutation (Q293X): rapid detection and characterization of defective post-transcriptional TLR/IL-1R responses in human myeloid and non-myeloid cells.
Davidson DJ, Currie AJ, Bowdish DM, Brown KL, Rosenberger CM, Ma RC, Bylund J, Campsall PA, Puel A, Picard C, Casanova JL, Turvey SE, Hancock RE, Devon RS, Speert DP. Davidson DJ, et al. Among authors: brown kl. J Immunol. 2006 Dec 1;177(11):8202-11. doi: 10.4049/jimmunol.177.11.8202. J Immunol. 2006. PMID: 17114497 Free PMC article.
Novel anti-infectives: is host defence the answer?
Hamill P, Brown K, Jenssen H, Hancock RE. Hamill P, et al. Curr Opin Biotechnol. 2008 Dec;19(6):628-36. doi: 10.1016/j.copbio.2008.10.006. Epub 2008 Nov 25. Curr Opin Biotechnol. 2008. PMID: 19000763 Review.
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