Brown RJ - Search Results

1

Impact of combined deficiency of hepatic lipase and endothelial lipase on the metabolism of both high-density lipoproteins and apolipoprotein B-containing lipoproteins.

Brown RJ, Lagor WR, Sankaranaravanan S, Yasuda T, Quertermous T, Rothblat GH, Rader DJ. Brown RJ, et al. Circ Res. 2010 Aug 6;107(3):357-64. doi: 10.1161/CIRCRESAHA.110.219188. Epub 2010 Jun 17. Circ Res. 2010. PMID: 20558822 Free PMC article.

2

Glycosylation of endothelial lipase at asparagine-116 reduces activity and the hydrolysis of native lipoproteins in vitro and in vivo.

Brown RJ, Miller GC, Griffon N, Long CJ, Rader DJ. Brown RJ, et al. J Lipid Res. 2007 May;48(5):1132-9. doi: 10.1194/jlr.M600535-JLR200. Epub 2007 Feb 24. J Lipid Res. 2007. PMID: 17322565 Free article.

3

Lipases as modulators of atherosclerosis in murine models.

Brown RJ, Rader DJ. Brown RJ, et al. Curr Drug Targets. 2007 Dec;8(12):1307-19. doi: 10.2174/138945007783220614. Curr Drug Targets. 2007. PMID: 18220707 Review.

4

Overexpression of apolipoprotein F reduces HDL cholesterol levels in vivo.

Lagor WR, Brown RJ, Toh SA, Millar JS, Fuki IV, de la Llera-Moya M, Yuen T, Rothblat G, Billheimer JT, Rader DJ. Lagor WR, et al. Among authors: brown rj. Arterioscler Thromb Vasc Biol. 2009 Jan;29(1):40-6. doi: 10.1161/ATVBAHA.108.177105. Epub 2008 Nov 13. Arterioscler Thromb Vasc Biol. 2009. PMID: 19008531 Free PMC article.

5

A naturally occurring variant of endothelial lipase associated with elevated HDL exhibits impaired synthesis.

Brown RJ, Edmondson AC, Griffon N, Hill TB, Fuki IV, Badellino KO, Li M, Wolfe ML, Reilly MP, Rader DJ. Brown RJ, et al. J Lipid Res. 2009 Sep;50(9):1910-6. doi: 10.1194/jlr.P900020-JLR200. Epub 2009 May 3. J Lipid Res. 2009. PMID: 19411705 Free PMC article.

6

When HDL gets fat..

Brown RJ, Rader DJ. Brown RJ, et al. Circ Res. 2008 Jul 18;103(2):131-2. doi: 10.1161/CIRCRESAHA.108.180638. Circ Res. 2008. PMID: 18635830 Free PMC article. No abstract available.

7

Loss-of-function variants in endothelial lipase are a cause of elevated HDL cholesterol in humans.

Edmondson AC, Brown RJ, Kathiresan S, Cupples LA, Demissie S, Manning AK, Jensen MK, Rimm EB, Wang J, Rodrigues A, Bamba V, Khetarpal SA, Wolfe ML, Derohannessian S, Li M, Reilly MP, Aberle J, Evans D, Hegele RA, Rader DJ. Edmondson AC, et al. Among authors: brown rj. J Clin Invest. 2009 Apr;119(4):1042-50. doi: 10.1172/JCI37176. Epub 2009 Mar 16. J Clin Invest. 2009. PMID: 19287092 Free PMC article.

8

Lipidomic analyses of female mice lacking hepatic lipase and endothelial lipase indicate selective modulation of plasma lipid species.

Yang Y, Kuwano T, Lagor WR, Albert CJ, Brenton S, Rader DJ, Ford DA, Brown RJ. Yang Y, et al. Among authors: brown rj. Lipids. 2014 Jun;49(6):505-15. doi: 10.1007/s11745-014-3907-6. Epub 2014 Apr 29. Lipids. 2014. PMID: 24777581 Free PMC article.

9

Can We Make High-Density Lipoproteins Great Again?

Thyagarajan N, Brannan AM, Brown RJ. Thyagarajan N, et al. Among authors: brown rj. Circulation. 2016 May 10;133(19):1833-5. doi: 10.1161/CIRCULATIONAHA.116.022593. Epub 2016 Apr 14. Circulation. 2016. PMID: 27081118 No abstract available.

10

Hydrolysis products generated by lipoprotein lipase and endothelial lipase differentially impact THP-1 macrophage cell signalling pathways.

Essaji Y, Yang Y, Albert CJ, Ford DA, Brown RJ. Essaji Y, et al. Among authors: brown rj. Lipids. 2013 Aug;48(8):769-778. doi: 10.1007/s11745-013-3810-6. Epub 2013 Jun 22. Lipids. 2013. PMID: 23794138 Free PMC article.

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