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Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy.
Bierhaus A, Fleming T, Stoyanov S, Leffler A, Babes A, Neacsu C, Sauer SK, Eberhardt M, Schnölzer M, Lasitschka F, Neuhuber WL, Kichko TI, Konrade I, Elvert R, Mier W, Pirags V, Lukic IK, Morcos M, Dehmer T, Rabbani N, Thornalley PJ, Edelstein D, Nau C, Forbes J, Humpert PM, Schwaninger M, Ziegler D, Stern DM, Cooper ME, Haberkorn U, Brownlee M, Reeh PW, Nawroth PP. Bierhaus A, et al. Among authors: brownlee m. Nat Med. 2012 Jun;18(6):926-33. doi: 10.1038/nm.2750. Nat Med. 2012. PMID: 22581285
Preventing kidney cell suicide.
Brownlee M. Brownlee M. Nat Med. 2007 Nov;13(11):1284-5. doi: 10.1038/nm1107-1284. Nat Med. 2007. PMID: 17987021 No abstract available.
Diabetic kidney disease.
Thomas MC, Brownlee M, Susztak K, Sharma K, Jandeleit-Dahm KA, Zoungas S, Rossing P, Groop PH, Cooper ME. Thomas MC, et al. Among authors: brownlee m. Nat Rev Dis Primers. 2015 Jul 30;1:15018. doi: 10.1038/nrdp.2015.18. Nat Rev Dis Primers. 2015. PMID: 27188921 Free PMC article. Review.
Glucose and diabetic vascular disease.
Ruderman NB, Williamson JR, Brownlee M. Ruderman NB, et al. Among authors: brownlee m. FASEB J. 1992 Aug;6(11):2905-14. doi: 10.1096/fasebj.6.11.1644256. FASEB J. 1992. PMID: 1644256 Review.
Negative consequences of glycation.
Brownlee M. Brownlee M. Metabolism. 2000 Feb;49(2 Suppl 1):9-13. doi: 10.1016/s0026-0495(00)80078-5. Metabolism. 2000. PMID: 10693913 Review.
220 results