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Biochemistry and molecular cell biology of diabetic complications.
Brownlee M. Brownlee M. Nature. 2001 Dec 13;414(6865):813-20. doi: 10.1038/414813a. Nature. 2001. PMID: 11742414
Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy.
Bierhaus A, Fleming T, Stoyanov S, Leffler A, Babes A, Neacsu C, Sauer SK, Eberhardt M, Schnölzer M, Lasitschka F, Neuhuber WL, Kichko TI, Konrade I, Elvert R, Mier W, Pirags V, Lukic IK, Morcos M, Dehmer T, Rabbani N, Thornalley PJ, Edelstein D, Nau C, Forbes J, Humpert PM, Schwaninger M, Ziegler D, Stern DM, Cooper ME, Haberkorn U, Brownlee M, Reeh PW, Nawroth PP. Bierhaus A, et al. Among authors: brownlee m. Nat Med. 2012 Jun;18(6):926-33. doi: 10.1038/nm.2750. Nat Med. 2012. PMID: 22581285
Preventing kidney cell suicide.
Brownlee M. Brownlee M. Nat Med. 2007 Nov;13(11):1284-5. doi: 10.1038/nm1107-1284. Nat Med. 2007. PMID: 17987021 No abstract available.
Diabetic kidney disease.
Thomas MC, Brownlee M, Susztak K, Sharma K, Jandeleit-Dahm KA, Zoungas S, Rossing P, Groop PH, Cooper ME. Thomas MC, et al. Among authors: brownlee m. Nat Rev Dis Primers. 2015 Jul 30;1:15018. doi: 10.1038/nrdp.2015.18. Nat Rev Dis Primers. 2015. PMID: 27188921 Review.
The cellular and molecular mechanisms of diabetic complications.
King GL, Brownlee M. King GL, et al. Among authors: brownlee m. Endocrinol Metab Clin North Am. 1996 Jun;25(2):255-70. doi: 10.1016/s0889-8529(05)70324-8. Endocrinol Metab Clin North Am. 1996. PMID: 8799700 Review.
Glycosylation products as toxic mediators of diabetic complications.
Brownlee M. Brownlee M. Annu Rev Med. 1991;42:159-66. doi: 10.1146/ Annu Rev Med. 1991. PMID: 2035962 Review.
Glucose and diabetic vascular disease.
Ruderman NB, Williamson JR, Brownlee M. Ruderman NB, et al. Among authors: brownlee m. FASEB J. 1992 Aug;6(11):2905-14. doi: 10.1096/fasebj.6.11.1644256. FASEB J. 1992. PMID: 1644256 Review.
Advanced products of nonenzymatic glycosylation and the pathogenesis of diabetic vascular disease.
Brownlee M, Cerami A, Vlassara H. Brownlee M, et al. Diabetes Metab Rev. 1988 Aug;4(5):437-51. doi: 10.1002/dmr.5610040503. Diabetes Metab Rev. 1988. PMID: 2850143 Review. No abstract available.
Negative consequences of glycation.
Brownlee M. Brownlee M. Metabolism. 2000 Feb;49(2 Suppl 1):9-13. doi: 10.1016/s0026-0495(00)80078-5. Metabolism. 2000. PMID: 10693913 Review.
Overexpression of glyoxalase-I in bovine endothelial cells inhibits intracellular advanced glycation endproduct formation and prevents hyperglycemia-induced increases in macromolecular endocytosis.
Shinohara M, Thornalley PJ, Giardino I, Beisswenger P, Thorpe SR, Onorato J, Brownlee M. Shinohara M, et al. Among authors: brownlee m. J Clin Invest. 1998 Mar 1;101(5):1142-7. doi: 10.1172/JCI119885. J Clin Invest. 1998. PMID: 9486985 Free PMC article.
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