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Peroxisome proliferator-activated-γ coactivator-1α-mediated mitochondrial biogenesis is important for hematopoietic recovery in response to stress.
Basu S, Broxmeyer HE, Hangoc G. Basu S, et al. Among authors: broxmeyer he. Stem Cells Dev. 2013 Jun 1;22(11):1678-92. doi: 10.1089/scd.2012.0466. Epub 2013 Feb 13. Stem Cells Dev. 2013. PMID: 23311338 Free PMC article.
Interleukin-6 ablates the accessory cell-mediated suppressive effects of lactoferrin on human hematopoietic progenitor cell proliferation in vitro.
Gentile P, Broxmeyer HE. Gentile P, et al. Among authors: broxmeyer he. Ann N Y Acad Sci. 1991;628:74-83. doi: 10.1111/j.1749-6632.1991.tb17225.x. Ann N Y Acad Sci. 1991. PMID: 2069324
Activation of OCT4 enhances ex vivo expansion of human cord blood hematopoietic stem and progenitor cells by regulating HOXB4 expression.
Huang X, Lee MR, Cooper S, Hangoc G, Hong KS, Chung HM, Broxmeyer HE. Huang X, et al. Among authors: broxmeyer he. Leukemia. 2016 Jan;30(1):144-53. doi: 10.1038/leu.2015.189. Epub 2015 Jul 23. Leukemia. 2016. PMID: 26202933 Free PMC article.
Cytokine-dependent ex vivo expansion of early subsets of CD34+ cord blood myeloid progenitors is enhanced by cord blood plasma, but expansion of the more mature subsets of progenitors is favored.
Ruggieri L, Heimfeld S, Broxmeyer HE. Ruggieri L, et al. Among authors: broxmeyer he. Blood Cells. 1994;20(2-3):436-54. Blood Cells. 1994. PMID: 7538350
Suppression of p53-mediated growth factor withdrawal-induced apoptosis in the myeloid compartment by hematopoietic cytokines: an overview of hematopoiesis and apoptosis with a presentation of thrombopoietin and the M07E cell line as a model system.
Ritchie A, Broxmeyer HE. Ritchie A, et al. Among authors: broxmeyer he. Crit Rev Oncol Hematol. 1999 Aug;31(3):169-91. doi: 10.1016/s1040-8428(99)00018-9. Crit Rev Oncol Hematol. 1999. PMID: 10532194 Review.
Altered responsiveness to chemokines due to targeted disruption of SHIP.
Kim CH, Hangoc G, Cooper S, Helgason CD, Yew S, Humphries RK, Krystal G, Broxmeyer HE. Kim CH, et al. Among authors: broxmeyer he. J Clin Invest. 1999 Dec;104(12):1751-9. doi: 10.1172/JCI7310. J Clin Invest. 1999. PMID: 10606629 Free PMC article.
Therapeutic potential of 4-1BB (CD137) as a regulator for effector CD8(+) T cells.
Kim YJ, Broxmeyer HE. Kim YJ, et al. Among authors: broxmeyer he. J Hematother Stem Cell Res. 2001 Aug;10(4):441-9. doi: 10.1089/15258160152509064. J Hematother Stem Cell Res. 2001. PMID: 11522228 Review.
Transcriptional and ERK1/2-dependent synergistic upregulation of p21(cip1/waf1) associated with steel factor synergy in MO7e.
Lee Y, Mantel C, Anzai N, Braun SE, Broxmeyer HE. Lee Y, et al. Among authors: broxmeyer he. Biochem Biophys Res Commun. 2001 Jan 26;280(3):675-83. doi: 10.1006/bbrc.2000.4215. Biochem Biophys Res Commun. 2001. PMID: 11162574
Differentially expressed genes during in vitro differentiation of murine embryonic stem cells transduced with a human erythropoietin receptor cDNA.
Xia ZB, Dai MS, Magoulas C, Broxmeyer HE, Lu L. Xia ZB, et al. Among authors: broxmeyer he. J Hematother Stem Cell Res. 2000 Oct;9(5):651-8. doi: 10.1089/15258160050196696. J Hematother Stem Cell Res. 2000. PMID: 11091489
Enhancement of proliferation and differentiation of erythroid progenitors by co-transduction of erythropoietin receptor and H-ras cDNAS into single CD34(3+) cord blood cells.
Lu L, Ge Y, Li ZH, Dai MS, Broxmeyer HE. Lu L, et al. Among authors: broxmeyer he. Bone Marrow Transplant. 2000 Oct;26(8):817-22. doi: 10.1038/sj.bmt.1702620. Bone Marrow Transplant. 2000. PMID: 11081379
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