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Protective anti-V antibodies inhibit Pseudomonas and Yersinia translocon assembly within host membranes.
Goure J, Broz P, Attree O, Cornelis GR, Attree I. Goure J, et al. Among authors: broz p. J Infect Dis. 2005 Jul 15;192(2):218-25. doi: 10.1086/430932. Epub 2005 Jun 7. J Infect Dis. 2005. PMID: 15962216
In the presence of antibodies against PcrV and Y. pestis LcrV, the hemolytic activity of P. aeruginosa was inhibited. Similarly, the hemolytic activity of Delta HOPEMN was inhibited in the presence of anti-LcrV antibodies. ...Thus, protective antibodies against the V antig …
In the presence of antibodies against PcrV and Y. pestis LcrV, the hemolytic activity of P. aeruginosa was inhibited. Similarly, the …
The V-antigen of Yersinia forms a distinct structure at the tip of injectisome needles.
Mueller CA, Broz P, Müller SA, Ringler P, Erne-Brand F, Sorg I, Kuhn M, Engel A, Cornelis GR. Mueller CA, et al. Among authors: broz p. Science. 2005 Oct 28;310(5748):674-6. doi: 10.1126/science.1118476. Science. 2005. PMID: 16254184
Function and molecular architecture of the Yersinia injectisome tip complex.
Broz P, Mueller CA, Müller SA, Philippsen A, Sorg I, Engel A, Cornelis GR. Broz P, et al. Mol Microbiol. 2007 Sep;65(5):1311-20. doi: 10.1111/j.1365-2958.2007.05871.x. Mol Microbiol. 2007. PMID: 17697254
YscU recognizes translocators as export substrates of the Yersinia injectisome.
Sorg I, Wagner S, Amstutz M, Müller SA, Broz P, Lussi Y, Engel A, Cornelis GR. Sorg I, et al. Among authors: broz p. EMBO J. 2007 Jun 20;26(12):3015-24. doi: 10.1038/sj.emboj.7601731. Epub 2007 May 17. EMBO J. 2007. PMID: 17510628 Free PMC article.
The needle length of bacterial injectisomes is determined by a molecular ruler.
Journet L, Agrain C, Broz P, Cornelis GR. Journet L, et al. Among authors: broz p. Science. 2003 Dec 5;302(5651):1757-60. doi: 10.1126/science.1091422. Science. 2003. PMID: 14657497
Inflammasomes: Intracellular detection of extracellular bacteria.
Broz P. Broz P. Cell Res. 2016 Aug;26(8):859-60. doi: 10.1038/cr.2016.67. Epub 2016 Jun 10. Cell Res. 2016. PMID: 27283800 Free PMC article.
ESCRT-dependent membrane repair negatively regulates pyroptosis downstream of GSDMD activation.
Rühl S, Shkarina K, Demarco B, Heilig R, Santos JC, Broz P. Rühl S, et al. Among authors: broz p. Science. 2018 Nov 23;362(6417):956-960. doi: 10.1126/science.aar7607. Science. 2018. PMID: 30467171
Immune Response: Intracellular pathogens under attack.
Broz P. Broz P. Elife. 2016 Feb 19;5:e14729. doi: 10.7554/eLife.14729. Elife. 2016. PMID: 26894956 Free PMC article.
Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases.
Meunier E, Dick MS, Dreier RF, Schürmann N, Kenzelmann Broz D, Warming S, Roose-Girma M, Bumann D, Kayagaki N, Takeda K, Yamamoto M, Broz P. Meunier E, et al. Among authors: broz p. Nature. 2014 May 15;509(7500):366-70. doi: 10.1038/nature13157. Epub 2014 Apr 16. Nature. 2014. PMID: 24739961
BAX/BAK-Induced Apoptosis Results in Caspase-8-Dependent IL-1β Maturation in Macrophages.
Chauhan D, Bartok E, Gaidt MM, Bock FJ, Herrmann J, Seeger JM, Broz P, Beckmann R, Kashkar H, Tait SWG, Müller R, Hornung V. Chauhan D, et al. Among authors: broz p. Cell Rep. 2018 Nov 27;25(9):2354-2368.e5. doi: 10.1016/j.celrep.2018.10.087. Cell Rep. 2018. PMID: 30485805
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