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Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1.
Broz P, Ruby T, Belhocine K, Bouley DM, Kayagaki N, Dixit VM, Monack DM. Broz P, et al. Nature. 2012 Oct 11;490(7419):288-91. doi: 10.1038/nature11419. Epub 2012 Aug 15. Nature. 2012. PMID: 22895188 Free PMC article.
Noncanonical inflammasomes: caspase-11 activation and effector mechanisms.
Broz P, Monack DM. Broz P, et al. PLoS Pathog. 2013 Feb;9(2):e1003144. doi: 10.1371/journal.ppat.1003144. Epub 2013 Feb 28. PLoS Pathog. 2013. PMID: 23468620 Free PMC article. No abstract available.
Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases.
Meunier E, Dick MS, Dreier RF, Schürmann N, Kenzelmann Broz D, Warming S, Roose-Girma M, Bumann D, Kayagaki N, Takeda K, Yamamoto M, Broz P. Meunier E, et al. Nature. 2014 May 15;509(7500):366-70. doi: 10.1038/nature13157. Epub 2014 Apr 16. Nature. 2014. PMID: 24739961
Guanylate-binding proteins promote activation of the AIM2 inflammasome during infection with Francisella novicida.
Meunier E, Wallet P, Dreier RF, Costanzo S, Anton L, Rühl S, Dussurgey S, Dick MS, Kistner A, Rigard M, Degrandi D, Pfeffer K, Yamamoto M, Henry T, Broz P. Meunier E, et al. Nat Immunol. 2015 May;16(5):476-484. doi: 10.1038/ni.3119. Epub 2015 Mar 16. Nat Immunol. 2015. PMID: 25774716 Free PMC article.
Caspase-11 activates a canonical NLRP3 inflammasome by promoting K(+) efflux.
Rühl S, Broz P. Rühl S, et al. Eur J Immunol. 2015 Oct;45(10):2927-36. doi: 10.1002/eji.201545772. Epub 2015 Aug 6. Eur J Immunol. 2015. PMID: 26173909
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