Brubaker D - Search Results

1

FREQUENT SUBGRAPH MINING OF PERSONALIZED SIGNALING PATHWAY NETWORKS GROUPS PATIENTS WITH FREQUENTLY DYSREGULATED DISEASE PATHWAYS AND PREDICTS PROGNOSIS.

Durmaz A, Henderson TAD, Brubaker D, Bebek G. Durmaz A, et al. Among authors: brubaker d. Pac Symp Biocomput. 2017;22:402-413. doi: 10.1142/9789813207813_0038. Pac Symp Biocomput. 2017. PMID: 27896993 Free PMC article.

2

Drug Intervention Response Predictions with PARADIGM (DIRPP) identifies drug resistant cancer cell lines and pathway mechanisms of resistance.

Brubaker D, Difeo A, Chen Y, Pearl T, Zhai K, Bebek G, Chance M, Barnholtz-Sloan J. Brubaker D, et al. Pac Symp Biocomput. 2014:125-35. Pac Symp Biocomput. 2014. PMID: 24297540 Free PMC article.

3

Finding lost genes in GWAS via integrative-omics analysis reveals novel sub-networks associated with preterm birth.

Brubaker D, Liu Y, Wang J, Tan H, Zhang G, Jacobsson B, Muglia L, Mesiano S, Chance MR. Brubaker D, et al. Hum Mol Genet. 2016 Dec 1;25(23):5254-5264. doi: 10.1093/hmg/ddw325. Hum Mol Genet. 2016. PMID: 27664809 Free PMC article.

4

Enhanced annotation of CD45RA to distinguish T cell subsets in single-cell RNA-seq via machine learning.

Ran R, Brubaker DK. Ran R, et al. Among authors: brubaker dk. Bioinform Adv. 2023 Nov 6;3(1):vbad159. doi: 10.1093/bioadv/vbad159. eCollection 2023. Bioinform Adv. 2023. PMID: 38023329 Free PMC article.

5

Integrated in vivo multiomics analysis identifies p21-activated kinase signaling as a driver of colitis.

Lyons J, Brubaker DK, Ghazi PC, Baldwin KR, Edwards A, Boukhali M, Strasser SD, Suarez-Lopez L, Lin YJ, Yajnik V, Kissil JL, Haas W, Lauffenburger DA, Haigis KM. Lyons J, et al. Sci Signal. 2018 Feb 27;11(519):eaan3580. doi: 10.1126/scisignal.aan3580. Sci Signal. 2018. PMID: 29487189 Free PMC article.

6

A dynamical systems model of progesterone receptor interactions with inflammation in human parturition.

Brubaker D, Barbaro A, R Chance M, Mesiano S. Brubaker D, et al. BMC Syst Biol. 2016 Aug 19;10(1):79. doi: 10.1186/s12918-016-0320-1. BMC Syst Biol. 2016. PMID: 27543267 Free PMC article.

7

Integrated microRNA and mRNA network analysis of the human myometrial transcriptome in the transition from quiescence to labor.

Ackerman WE 4th, Buhimschi IA, Brubaker D, Maxwell S, Rood KM, Chance MR, Jing H, Mesiano S, Buhimschi CS. Ackerman WE 4th, et al. Among authors: brubaker d. Biol Reprod. 2018 Jun 1;98(6):834-845. doi: 10.1093/biolre/ioy040. Biol Reprod. 2018. PMID: 29447339 Free PMC article.

8

Computational translation of genomic responses from experimental model systems to humans.

Brubaker DK, Proctor EA, Haigis KM, Lauffenburger DA. Brubaker DK, et al. PLoS Comput Biol. 2019 Jan 10;15(1):e1006286. doi: 10.1371/journal.pcbi.1006286. eCollection 2019 Jan. PLoS Comput Biol. 2019. PMID: 30629591 Free PMC article.

9

Tissue-Specific Oncogenic Activity of KRAS^A146T.

Poulin EJ, Bera AK, Lu J, Lin YJ, Strasser SD, Paulo JA, Huang TQ, Morales C, Yan W, Cook J, Nowak JA, Brubaker DK, Joughin BA, Johnson CW, DeStefanis RA, Ghazi PC, Gondi S, Wales TE, Iacob RE, Bogdanova L, Gierut JJ, Li Y, Engen JR, Perez-Mancera PA, Braun BS, Gygi SP, Lauffenburger DA, Westover KD, Haigis KM. Poulin EJ, et al. Among authors: brubaker dk. Cancer Discov. 2019 Jun;9(6):738-755. doi: 10.1158/2159-8290.CD-18-1220. Epub 2019 Apr 5. Cancer Discov. 2019. PMID: 30952657 Free PMC article.

10

Proteogenomic Network Analysis of Context-Specific KRAS Signaling in Mouse-to-Human Cross-Species Translation.

Brubaker DK, Paulo JA, Sheth S, Poulin EJ, Popow O, Joughin BA, Strasser SD, Starchenko A, Gygi SP, Lauffenburger DA, Haigis KM. Brubaker DK, et al. Cell Syst. 2019 Sep 25;9(3):258-270.e6. doi: 10.1016/j.cels.2019.07.006. Epub 2019 Sep 11. Cell Syst. 2019. PMID: 31521603 Free PMC article.

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