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Anthracycline-derived chemotherapeutics in apoptosis and free radical cytotoxicity (Review).
Müller I, Niethammer D, Bruchelt G. Müller I, et al. Int J Mol Med. 1998 Feb;1(2):491-4. doi: 10.3892/ijmm.1.2.491. Int J Mol Med. 1998. PMID: 9852255 Review.
Here, mechanistic aspects for successful cytostasis and for side effects, e.g. cardiomyopathy, are discussed. We emphasize recent developments in anthracycline-mediated apoptosis and focus on a well known representative, doxorubicin (adriamycin, adriblastin). ...
Here, mechanistic aspects for successful cytostasis and for side effects, e.g. cardiomyopathy, are discussed. We emphasize recent dev …
Influence of dichloroacetate (DCA) on lactate production and oxygen consumption in neuroblastoma cells: is DCA a suitable drug for neuroblastoma therapy?
Niewisch MR, Kuçi Z, Wolburg H, Sautter M, Krampen L, Deubzer B, Handgretinger R, Bruchelt G. Niewisch MR, et al. Among authors: bruchelt g. Cell Physiol Biochem. 2012;29(3-4):373-80. doi: 10.1159/000338492. Epub 2012 Apr 3. Cell Physiol Biochem. 2012. PMID: 22508045 Free article.
Low-density lipoprotein modification by normal, myeloperoxidase-deficient and NADPH oxidase-deficient granulocytes and the impact of redox active transition metal ions.
Gerber CE, Bruchelt G, Ledinski G, Greilberger J, Niethammer D, Jürgens G. Gerber CE, et al. Redox Rep. 2002;7(2):111-9. doi: 10.1179/135100002125000343. Redox Rep. 2002. PMID: 12189057
H(2)O(2)-mediated cytotoxicity of pharmacologic ascorbate concentrations to neuroblastoma cells: potential role of lactate and ferritin.
Deubzer B, Mayer F, Kuçi Z, Niewisch M, Merkel G, Handgretinger R, Bruchelt G. Deubzer B, et al. Cell Physiol Biochem. 2010;25(6):767-74. doi: 10.1159/000315098. Epub 2010 May 18. Cell Physiol Biochem. 2010. PMID: 20511723
Chemotactic activity of substances derived from antibody-loaded tumor cells on granulocytes.
Schaber B, Bruchelt G, Meyle J, Jeschke B, Handgretinger R, Niethammer D, Mayer P, Rassner G, Fierlbeck G. Schaber B, et al. Immunol Lett. 1994 Jun;41(1):67-71. doi: 10.1016/0165-2478(94)90058-2. Immunol Lett. 1994. PMID: 7959905
Nifurtimox reduces N-Myc expression and aerobic glycolysis in neuroblastoma.
Cabanillas Stanchi KM, Bruchelt G, Handgretinger R, Holzer U. Cabanillas Stanchi KM, et al. Among authors: bruchelt g. Cancer Biol Ther. 2015;16(9):1353-63. doi: 10.1080/15384047.2015.1070987. Epub 2015 Jul 15. Cancer Biol Ther. 2015. PMID: 26177922 Free PMC article.
6-fluorodopamine selectively destroys neuroblastoma cells expressing the noradrenaline transporter.
Seitz G, Bruchelt G, Kuci Z, Roginsky VA, Wolburg H, Stegmann HB, Niethammer D. Seitz G, et al. Med Pediatr Oncol. 2000 Dec;35(6):612-5. doi: 10.1002/1096-911x(20001201)35:6<612::aid-mpo26>3.0.co;2-u. Med Pediatr Oncol. 2000. PMID: 11107129
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