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1988 1
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2005 11
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Page 1
Clinical Spectrum of SCN5A Mutations: Long QT Syndrome, Brugada Syndrome, and Cardiomyopathy.
Wilde AAM, Amin AS. Wilde AAM, et al. JACC Clin Electrophysiol. 2018 May;4(5):569-579. doi: 10.1016/j.jacep.2018.03.006. Epub 2018 May 2. JACC Clin Electrophysiol. 2018. PMID: 29798782 Free article. Review.
The importance of Na(v)1.5 for normal cardiac electricity is reflected by various disease entities that can be caused by mutations in SCN5A. Gain-of-function mutations in SCN5A lead to more sodium influx into cardiomyocytes through aberrant channel gating and cause long QT …
The importance of Na(v)1.5 for normal cardiac electricity is reflected by various disease entities that can be caused by mutations in …
Brugada syndrome.
Korlipara H, Korlipara G, Pentyala S. Korlipara H, et al. Acta Cardiol. 2021 Oct;76(8):805-824. doi: 10.1080/00015385.2020.1790823. Epub 2020 Jul 20. Acta Cardiol. 2021. PMID: 32684122 Review.
Brugada syndrome (BrS) is an inherited cardiac arrhythmia syndrome that causes a heightened risk for ventricular tachyarrhythmias and sudden cardiac death. ...Diagnosis of BrS in patients currently relies on presentation with a type-1 Brugada pattern o
Brugada syndrome (BrS) is an inherited cardiac arrhythmia syndrome that causes a heightened risk for ventricular tachya
Risk factors for QTc-prolongation: systematic review of the evidence.
Vandael E, Vandenberk B, Vandenberghe J, Willems R, Foulon V. Vandael E, et al. Int J Clin Pharm. 2017 Feb;39(1):16-25. doi: 10.1007/s11096-016-0414-2. Epub 2016 Dec 23. Int J Clin Pharm. 2017. PMID: 28012118 Review.
Results Ten observational studies could be included, with a total of 89,532 patients [prospective cohort design: N = 6; multiple regression analyses: N = 5; median STROBE score = 17/22 (range 15-18)]. Very strong evidence was found for hypokalemia, use of diuretics, antiar …
Results Ten observational studies could be included, with a total of 89,532 patients [prospective cohort design: N = 6; multiple regression …
Brugada syndrome.
Brugada R, Campuzano O, Sarquella-Brugada G, Brugada J, Brugada P. Brugada R, et al. Methodist Debakey Cardiovasc J. 2014 Jan-Mar;10(1):25-8. doi: 10.14797/mdcj-10-1-25. Methodist Debakey Cardiovasc J. 2014. PMID: 24932359 Free PMC article. Review.
Brugada syndrome is a rare cardiac arrhythmia characterized by electrocardiographic right bundle branch block and persistent ST-segment elevation in the right precordial leads. ...This brief review focuses on the recent clinical diagnosis, genetic basis, and advance
Brugada syndrome is a rare cardiac arrhythmia characterized by electrocardiographic right bundle branch block and persistent S
The Genetics of Brugada Syndrome.
Cerrone M, Costa S, Delmar M. Cerrone M, et al. Annu Rev Genomics Hum Genet. 2022 Aug 31;23:255-274. doi: 10.1146/annurev-genom-112921-011200. Epub 2022 May 13. Annu Rev Genomics Hum Genet. 2022. PMID: 35567276 Free article. Review.
Brugada syndrome is a heritable channelopathy characterized by a peculiar electrocardiogram (ECG) pattern and increased risk of cardiac arrhythmias and sudden death. ...Even if an overt structural cardiomyopathy is not typical of Brugada syndrome, fibr
Brugada syndrome is a heritable channelopathy characterized by a peculiar electrocardiogram (ECG) pattern and increased risk o
Spotlight on the 2022 ESC guideline management of ventricular arrhythmias and prevention of sudden cardiac death: 10 novel key aspects.
Könemann H, Dagres N, Merino JL, Sticherling C, Zeppenfeld K, Tfelt-Hansen J, Eckardt L. Könemann H, et al. Europace. 2023 May 19;25(5):euad091. doi: 10.1093/europace/euad091. Europace. 2023. PMID: 37102266 Free PMC article. Review.
Regarding sudden cardiac death risk stratification, risk calculators for laminopathies, and long QT syndrome are now considered besides the already established risk calculator for hypertrophic cardiomyopathy. Generally, 'new' risk markers beyond left ventricular ejection f …
Regarding sudden cardiac death risk stratification, risk calculators for laminopathies, and long QT syndrome are now considered besid …
Brugada syndrome, exercise, and exercise testing.
Masrur S, Memon S, Thompson PD. Masrur S, et al. Clin Cardiol. 2015 May;38(5):323-6. doi: 10.1002/clc.22386. Epub 2015 May 8. Clin Cardiol. 2015. PMID: 25955277 Free PMC article. Review.
We identified 98 English-language articles possibly addressing exercise in Brugada syndrome by searching PubMed and Google Scholar from January 1990 through November 2013 using the keywords "Brugada syndrome," "exercise," "exercise testing," and "synco …
We identified 98 English-language articles possibly addressing exercise in Brugada syndrome by searching PubMed and Google Sch …
Brugada syndrome.
Mizusawa Y, Wilde AA. Mizusawa Y, et al. Circ Arrhythm Electrophysiol. 2012 Jun 1;5(3):606-16. doi: 10.1161/CIRCEP.111.964577. Circ Arrhythm Electrophysiol. 2012. PMID: 22715240 Review. No abstract available.
The Brugada syndrome.
Escárcega RO, Jiménez-Hernández M, Garcia-Carrasco M, Perez-Alva JC, Brugada J. Escárcega RO, et al. Acta Cardiol. 2009 Dec;64(6):795-801. doi: 10.2143/AC.64.6.2044745. Acta Cardiol. 2009. PMID: 20128157 Review.
The genetic abnormalities that cause Brugada syndrome have been linked to mutations in the ion channel gene SCN5A which encodes for the alpha-subunit of the cardiac sodium channel. A consensus conference report published in 2002 described the diagnostic criteria for …
The genetic abnormalities that cause Brugada syndrome have been linked to mutations in the ion channel gene SCN5A which encode …
Experimental Models of Brugada syndrome.
Sendfeld F, Selga E, Scornik FS, Pérez GJ, Mills NL, Brugada R. Sendfeld F, et al. Int J Mol Sci. 2019 Apr 29;20(9):2123. doi: 10.3390/ijms20092123. Int J Mol Sci. 2019. PMID: 31032819 Free PMC article. Review.
Brugada syndrome is an inherited, rare cardiac arrhythmogenic disease, associated with sudden cardiac death. ...The recent development of pluripotent stem cell technology creates an opportunity to study cardiomyocytes derived from patients and healthy individuals. T
Brugada syndrome is an inherited, rare cardiac arrhythmogenic disease, associated with sudden cardiac death. ...The recent dev
195 results