Brugarolas J - Search Results

1

Radiation-induced cell cycle arrest compromised by p21 deficiency.

Brugarolas J, Chandrasekaran C, Gordon JI, Beach D, Jacks T, Hannon GJ. Brugarolas J, et al. Nature. 1995 Oct 12;377(6549):552-7. doi: 10.1038/377552a0. Nature. 1995. PMID: 7566157

2

Transcriptional activation by p53, but not induction of the p21 gene, is essential for oncogene-mediated apoptosis.

Attardi LD, Lowe SW, Brugarolas J, Jacks T. Attardi LD, et al. Among authors: brugarolas j. EMBO J. 1996 Jul 15;15(14):3693-701. EMBO J. 1996. PMID: 8758936 Free PMC article.

3

Double indemnity: p53, BRCA and cancer. p53 mutation partially rescues developmental arrest in Brca1 and Brca2 null mice, suggesting a role for familial breast cancer genes in DNA damage repair.

Brugarolas J, Jacks T. Brugarolas J, et al. Nat Med. 1997 Jul;3(7):721-2. doi: 10.1038/nm0797-721. Nat Med. 1997. PMID: 9212093 No abstract available.

4

Deletion of p21 cannot substitute for p53 loss in rescue of mdm2 null lethality.

Montes de Oca Luna R, Amelse LL, Chavez-Reyes A, Evans SC, Brugarolas J, Jacks T, Lozano G. Montes de Oca Luna R, et al. Among authors: brugarolas j. Nat Genet. 1997 Aug;16(4):336-7. doi: 10.1038/ng0897-336. Nat Genet. 1997. PMID: 9241268 No abstract available.

5

p21 is a critical CDK2 regulator essential for proliferation control in Rb-deficient cells.

Brugarolas J, Bronson RT, Jacks T. Brugarolas J, et al. J Cell Biol. 1998 Apr 20;141(2):503-14. doi: 10.1083/jcb.141.2.503. J Cell Biol. 1998. PMID: 9548727 Free PMC article.

6

Involvement of p53 and p21 in cellular defects and tumorigenesis in Atm-/- mice.

Xu Y, Yang EM, Brugarolas J, Jacks T, Baltimore D. Xu Y, et al. Among authors: brugarolas j. Mol Cell Biol. 1998 Jul;18(7):4385-90. doi: 10.1128/MCB.18.7.4385. Mol Cell Biol. 1998. PMID: 9632822 Free PMC article.

7

Inhibition of cyclin-dependent kinase 2 by p21 is necessary for retinoblastoma protein-mediated G1 arrest after gamma-irradiation.

Brugarolas J, Moberg K, Boyd SD, Taya Y, Jacks T, Lees JA. Brugarolas J, et al. Proc Natl Acad Sci U S A. 1999 Feb 2;96(3):1002-7. doi: 10.1073/pnas.96.3.1002. Proc Natl Acad Sci U S A. 1999. PMID: 9927683 Free PMC article.

8

mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways.

Majumder PK, Febbo PG, Bikoff R, Berger R, Xue Q, McMahon LM, Manola J, Brugarolas J, McDonnell TJ, Golub TR, Loda M, Lane HA, Sellers WR. Majumder PK, et al. Among authors: brugarolas j. Nat Med. 2004 Jun;10(6):594-601. doi: 10.1038/nm1052. Epub 2004 May 23. Nat Med. 2004. PMID: 15156201

9

The cyclin kinase inhibitor p21CIP1/WAF1 limits glomerular epithelial cell proliferation in experimental glomerulonephritis.

Kim YG, Alpers CE, Brugarolas J, Johnson RJ, Couser WG, Shankland SJ. Kim YG, et al. Among authors: brugarolas j. Kidney Int. 1999 Jun;55(6):2349-61. doi: 10.1046/j.1523-1755.1999.00504.x. Kidney Int. 1999. PMID: 10354282 Free article.

10

Spectrum of diverse genomic alterations define non-clear cell renal carcinoma subtypes.

Durinck S, Stawiski EW, Pavía-Jiménez A, Modrusan Z, Kapur P, Jaiswal BS, Zhang N, Toffessi-Tcheuyap V, Nguyen TT, Pahuja KB, Chen YJ, Saleem S, Chaudhuri S, Heldens S, Jackson M, Peña-Llopis S, Guillory J, Toy K, Ha C, Harris CJ, Holloman E, Hill HM, Stinson J, Rivers CS, Janakiraman V, Wang W, Kinch LN, Grishin NV, Haverty PM, Chow B, Gehring JS, Reeder J, Pau G, Wu TD, Margulis V, Lotan Y, Sagalowsky A, Pedrosa I, de Sauvage FJ, Brugarolas J, Seshagiri S. Durinck S, et al. Among authors: brugarolas j. Nat Genet. 2015 Jan;47(1):13-21. doi: 10.1038/ng.3146. Epub 2014 Nov 17. Nat Genet. 2015. PMID: 25401301 Free PMC article.

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