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Haploid genetic screens in human cells identify host factors used by pathogens.
Carette JE, Guimaraes CP, Varadarajan M, Park AS, Wuethrich I, Godarova A, Kotecki M, Cochran BH, Spooner E, Ploegh HL, Brummelkamp TR. Carette JE, et al. Among authors: brummelkamp tr. Science. 2009 Nov 27;326(5957):1231-5. doi: 10.1126/science.1178955. Science. 2009. PMID: 19965467
Attachment of Chlamydia trachomatis L2 to host cells requires sulfation.
Rosmarin DM, Carette JE, Olive AJ, Starnbach MN, Brummelkamp TR, Ploegh HL. Rosmarin DM, et al. Among authors: brummelkamp tr. Proc Natl Acad Sci U S A. 2012 Jun 19;109(25):10059-64. doi: 10.1073/pnas.1120244109. Epub 2012 Jun 6. Proc Natl Acad Sci U S A. 2012. PMID: 22675117 Free PMC article.
Gene essentiality and synthetic lethality in haploid human cells.
Blomen VA, Májek P, Jae LT, Bigenzahn JW, Nieuwenhuis J, Staring J, Sacco R, van Diemen FR, Olk N, Stukalov A, Marceau C, Janssen H, Carette JE, Bennett KL, Colinge J, Superti-Furga G, Brummelkamp TR. Blomen VA, et al. Among authors: brummelkamp tr. Science. 2015 Nov 27;350(6264):1092-6. doi: 10.1126/science.aac7557. Epub 2015 Oct 15. Science. 2015. PMID: 26472760
Deciphering the glycosylome of dystroglycanopathies using haploid screens for lassa virus entry.
Jae LT, Raaben M, Riemersma M, van Beusekom E, Blomen VA, Velds A, Kerkhoven RM, Carette JE, Topaloglu H, Meinecke P, Wessels MW, Lefeber DJ, Whelan SP, van Bokhoven H, Brummelkamp TR. Jae LT, et al. Among authors: brummelkamp tr. Science. 2013 Apr 26;340(6131):479-83. doi: 10.1126/science.1233675. Epub 2013 Mar 21. Science. 2013. PMID: 23519211 Free PMC article.
105 results