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Accumulation of ubiquitin conjugates in a polyglutamine disease model occurs without global ubiquitin/proteasome system impairment.
Maynard CJ, Böttcher C, Ortega Z, Smith R, Florea BI, Díaz-Hernández M, Brundin P, Overkleeft HS, Li JY, Lucas JJ, Dantuma NP. Maynard CJ, et al. Proc Natl Acad Sci U S A. 2009 Aug 18;106(33):13986-91. doi: 10.1073/pnas.0906463106. Epub 2009 Jul 30. Proc Natl Acad Sci U S A. 2009. PMID: 19666572 Free PMC article.
Prion-like transmission of protein aggregates in neurodegenerative diseases.
Brundin P, Melki R, Kopito R. Brundin P, et al. Nat Rev Mol Cell Biol. 2010 Apr;11(4):301-7. doi: 10.1038/nrm2873. Nat Rev Mol Cell Biol. 2010. PMID: 20308987 Free PMC article. Review.
Neuronal properties, in vivo effects, and pathology of a Huntington's disease patient-derived induced pluripotent stem cells.
Jeon I, Lee N, Li JY, Park IH, Park KS, Moon J, Shim SH, Choi C, Chang DJ, Kwon J, Oh SH, Shin DA, Kim HS, Do JT, Lee DR, Kim M, Kang KS, Daley GQ, Brundin P, Song J. Jeon I, et al. Stem Cells. 2012 Sep;30(9):2054-62. doi: 10.1002/stem.1135. Stem Cells. 2012. PMID: 22628015
IGF-1 protects against diabetic features in an in vivo model of Huntington's disease.
Duarte AI, Petit GH, Ranganathan S, Li JY, Oliveira CR, Brundin P, Björkqvist M, Rego AC. Duarte AI, et al. Exp Neurol. 2011 Oct;231(2):314-9. doi: 10.1016/j.expneurol.2011.06.016. Epub 2011 Jul 7. Exp Neurol. 2011. PMID: 21763311
Extensive graft-derived dopaminergic innervation is maintained 24 years after transplantation in the degenerating parkinsonian brain.
Li W, Englund E, Widner H, Mattsson B, van Westen D, Lätt J, Rehncrona S, Brundin P, Björklund A, Lindvall O, Li JY. Li W, et al. Proc Natl Acad Sci U S A. 2016 Jun 7;113(23):6544-9. doi: 10.1073/pnas.1605245113. Epub 2016 May 2. Proc Natl Acad Sci U S A. 2016. PMID: 27140603 Free PMC article.
Caspase signalling controls microglia activation and neurotoxicity.
Burguillos MA, Deierborg T, Kavanagh E, Persson A, Hajji N, Garcia-Quintanilla A, Cano J, Brundin P, Englund E, Venero JL, Joseph B. Burguillos MA, et al. Nature. 2011 Apr 21;472(7343):319-24. doi: 10.1038/nature09788. Epub 2011 Mar 9. Nature. 2011. PMID: 21389984
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