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177 results
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Photo-oxidative disruption of lysosomal membranes causes apoptosis of cultured human fibroblasts.
Brunk UT, Dalen H, Roberg K, Hellquist HB. Brunk UT, et al. Free Radic Biol Med. 1997;23(4):616-26. doi: 10.1016/s0891-5849(97)00007-5. Free Radic Biol Med. 1997. PMID: 9215807
Lipofuscin-formation in cultured retinal pigment epithelial cells is related to their melanin content.
Sundelin SP, Nilsson SE, Brunk UT. Sundelin SP, et al. Among authors: brunk ut. Free Radic Biol Med. 2001 Jan 1;30(1):74-81. doi: 10.1016/s0891-5849(00)00444-5. Free Radic Biol Med. 2001. PMID: 11134897
Induction of lysosomal membrane permeabilization by compounds that activate p53-independent apoptosis.
Erdal H, Berndtsson M, Castro J, Brunk U, Shoshan MC, Linder S. Erdal H, et al. Proc Natl Acad Sci U S A. 2005 Jan 4;102(1):192-7. doi: 10.1073/pnas.0408592102. Epub 2004 Dec 23. Proc Natl Acad Sci U S A. 2005. PMID: 15618392 Free PMC article.
Antitumor activity of metal-chelating compound Dp44mT is mediated by formation of a redox-active copper complex that accumulates in lysosomes.
Lovejoy DB, Jansson PJ, Brunk UT, Wong J, Ponka P, Richardson DR. Lovejoy DB, et al. Among authors: brunk ut. Cancer Res. 2011 Sep 1;71(17):5871-80. doi: 10.1158/0008-5472.CAN-11-1218. Epub 2011 Jul 12. Cancer Res. 2011. PMID: 21750178 Free article.
Autophagy of HSP70 and chelation of lysosomal iron in a non-redox-active form.
Kurz T, Brunk UT. Kurz T, et al. Among authors: brunk ut. Autophagy. 2009 Jan;5(1):93-5. doi: 10.4161/auto.5.1.7248. Autophagy. 2009. PMID: 18989099
Insulinoma cells in culture show pronounced sensitivity to alloxan-induced oxidative stress.
Zhang H, Ollinger K, Brunk U. Zhang H, et al. Diabetologia. 1995 Jun;38(6):635-41. doi: 10.1007/BF00401832. Diabetologia. 1995. PMID: 7672482
Influence of dolichol on microsomal membrane functions.
Aberg F, Jakobsson-Borin A, Olsson M, Brunk U, Dallner G. Aberg F, et al. Cell Mol Biol (Noisy-le-grand). 1996 Jul;42(5):683-90. Cell Mol Biol (Noisy-le-grand). 1996. PMID: 8832099
One-electron transfer reactions of diquat radical to different reduction intermediates of oxygen. Formation of hydroxyl radical and electronically excited states.
Mira D, Brunk U, Boveris A, Cadenas E. Mira D, et al. Free Radic Biol Med. 1988;5(3):155-63. doi: 10.1016/0891-5849(88)90078-0. Free Radic Biol Med. 1988. PMID: 2855422
H2O2-mediated damage to lysosomal membranes of J-774 cells.
Zdolsek J, Zhang H, Roberg K, Brunk U. Zdolsek J, et al. Free Radic Res Commun. 1993;18(2):71-85. doi: 10.3109/10715769309147344. Free Radic Res Commun. 1993. PMID: 8386686
Redox activity within the lysosomal compartment: implications for aging and apoptosis.
Kurz T, Eaton JW, Brunk UT. Kurz T, et al. Among authors: brunk ut. Antioxid Redox Signal. 2010 Aug 15;13(4):511-23. doi: 10.1089/ars.2009.3005. Antioxid Redox Signal. 2010. PMID: 20039839 Review.
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