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Adipocyte-specific deletion of IL-6 does not attenuate obesity-induced weight gain or glucose intolerance in mice.
Whitham M, Pal M, Petzold T, Hjorth M, Egan CL, Brunner JS, Estevez E, Iliades P, Zivanovic B, Reibe S, Hughes WE, Findeisen M, Hidalgo J, Febbraio MA. Whitham M, et al. Among authors: brunner js. Am J Physiol Endocrinol Metab. 2019 Oct 1;317(4):E597-E604. doi: 10.1152/ajpendo.00206.2019. Epub 2019 Aug 6. Am J Physiol Endocrinol Metab. 2019. PMID: 31386565 Free article.
The PI3K pathway preserves metabolic health through MARCO-dependent lipid uptake by adipose tissue macrophages.
Brunner JS, Vogel A, Lercher A, Caldera M, Korosec A, Pühringer M, Hofmann M, Hajto A, Kieler M, Garrido LQ, Kerndl M, Kuttke M, Mesteri I, Górna MW, Kulik M, Dominiak PM, Brandon AE, Estevez E, Egan CL, Gruber F, Schweiger M, Menche J, Bergthaler A, Weichhart T, Klavins K, Febbraio MA, Sharif O, Schabbauer G. Brunner JS, et al. Nat Metab. 2020 Dec;2(12):1427-1442. doi: 10.1038/s42255-020-00311-5. Epub 2020 Nov 16. Nat Metab. 2020. PMID: 33199895
Beneficial Metabolic Effects of TREM2 in Obesity Are Uncoupled From Its Expression on Macrophages.
Sharif O, Brunner JS, Korosec A, Martins R, Jais A, Snijder B, Vogel A, Caldera M, Hladik A, Lakovits K, Saluzzo S, Boehm B, Gorki AD, Mesteri I, Lindroos-Christensen J, Tillmann K, Stoiber D, Menche J, Schabbauer G, Bilban M, Superti-Furga G, Esterbauer H, Knapp S. Sharif O, et al. Among authors: brunner js. Diabetes. 2021 Sep;70(9):2042-2057. doi: 10.2337/db20-0572. Epub 2021 Feb 24. Diabetes. 2021. PMID: 33627323 Free PMC article.
PI3K Signaling in Dendritic Cells Aggravates DSS-Induced Colitis.
Kuttke M, Hromadová D, Yildirim C, Brunner JS, Vogel A, Paar H, Peters S, Weber M, Hofmann M, Kerndl M, Kieler M, Datler H, Musiejovsky L, Salzmann M, Lang M, Soukup K, Halfmann A, Sharif O, Schabbauer G. Kuttke M, et al. Among authors: brunner js. Front Immunol. 2022 Apr 19;13:695576. doi: 10.3389/fimmu.2022.695576. eCollection 2022. Front Immunol. 2022. PMID: 35514976 Free PMC article.
Macrophage Rewiring by Nutrient Associated PI3K Dependent Pathways.
Sharif O, Brunner JS, Vogel A, Schabbauer G. Sharif O, et al. Among authors: brunner js. Front Immunol. 2019 Aug 21;10:2002. doi: 10.3389/fimmu.2019.02002. eCollection 2019. Front Immunol. 2019. PMID: 31497027 Free PMC article. Review.
Loss of Phosphatase and Tensin Homolog in APCs Impedes Th17-Mediated Autoimmune Encephalomyelitis.
Sahin E, Brunner JS, Kral JB, Kuttke M, Hanzl L, Datler H, Paar H, Neuwinger N, Saferding V, Zinser E, Halfmann A, Soukup K, Hainzl E, Lohmeyer T, Niederreiter B, Haider T, Dohnal AM, Krönke G, Blüml S, Schabbauer G. Sahin E, et al. Among authors: brunner js. J Immunol. 2015 Sep 15;195(6):2560-70. doi: 10.4049/jimmunol.1402511. Epub 2015 Aug 5. J Immunol. 2015. PMID: 26246144
Loss of phosphatase and tensin homolog (PTEN) in myeloid cells controls inflammatory bone destruction by regulating the osteoclastogenic potential of myeloid cells.
Blüml S, Friedrich M, Lohmeyer T, Sahin E, Saferding V, Brunner J, Puchner A, Mandl P, Niederreiter B, Smolen JS, Schabbauer G, Redlich K. Blüml S, et al. Among authors: brunner j. Ann Rheum Dis. 2015 Jan;74(1):227-33. doi: 10.1136/annrheumdis-2013-203486. Epub 2013 Sep 27. Ann Rheum Dis. 2015. PMID: 24078675
MicroRNA-155 Controls T Helper Cell Activation During Viral Infection.
Goncalves-Alves E, Saferding V, Schliehe C, Benson R, Kurowska-Stolarska M, Brunner JS, Puchner A, Podesser BK, Smolen JS, Redlich K, Bonelli M, Brewer J, Bergthaler A, Steiner G, Blüml S. Goncalves-Alves E, et al. Among authors: brunner js. Front Immunol. 2019 Jun 13;10:1367. doi: 10.3389/fimmu.2019.01367. eCollection 2019. Front Immunol. 2019. PMID: 31275315 Free PMC article.
37 results