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Cytosolic 5'-nucleotidase 1A is overexpressed in pancreatic cancer and mediates gemcitabine resistance by reducing intracellular gemcitabine metabolites.
Patzak MS, Kari V, Patil S, Hamdan FH, Goetze RG, Brunner M, Gaedcke J, Kitz J, Jodrell DI, Richards FM, Pilarsky C, Gruetzmann R, Rümmele P, Knösel T, Hessmann E, Ellenrieder V, Johnsen SA, Neesse A. Patzak MS, et al. Among authors: brunner m. EBioMedicine. 2019 Feb;40:394-405. doi: 10.1016/j.ebiom.2019.01.037. Epub 2019 Jan 30. EBioMedicine. 2019. PMID: 30709769 Free PMC article.
EZH2 Regulates Pancreatic Cancer Subtype Identity and Tumor Progression via Transcriptional Repression of GATA6.
Patil S, Steuber B, Kopp W, Kari V, Urbach L, Wang X, Küffer S, Bohnenberger H, Spyropoulou D, Zhang Z, Versemann L, Bösherz MS, Brunner M, Gaedcke J, Ströbel P, Zhang JS, Neesse A, Ellenrieder V, Singh SK, Johnsen SA, Hessmann E. Patil S, et al. Among authors: brunner m. Cancer Res. 2020 Nov 1;80(21):4620-4632. doi: 10.1158/0008-5472.CAN-20-0672. Epub 2020 Sep 9. Cancer Res. 2020. PMID: 32907838
Axon guidance receptor ROBO3 modulates subtype identity and prognosis via AXL-associated inflammatory network in pancreatic cancer.
Krebs N, Klein L, Wegwitz F, Espinet E, Maurer HC, Tu M, Penz F, Küffer S, Xu X, Bohnenberger H, Cameron S, Brunner M, Neesse A, Kishore U, Hessmann E, Trumpp A, Ströbel P, Brekken RA, Ellenrieder V, Singh SK. Krebs N, et al. Among authors: brunner m. JCI Insight. 2022 Aug 22;7(16):e154475. doi: 10.1172/jci.insight.154475. JCI Insight. 2022. PMID: 35993361 Free PMC article.
Inflammation-induced NFATc1-STAT3 transcription complex promotes pancreatic cancer initiation by KrasG12D.
Baumgart S, Chen NM, Siveke JT, König A, Zhang JS, Singh SK, Wolf E, Bartkuhn M, Esposito I, Heßmann E, Reinecke J, Nikorowitsch J, Brunner M, Singh G, Fernandez-Zapico ME, Smyrk T, Bamlet WR, Eilers M, Neesse A, Gress TM, Billadeau DD, Tuveson D, Urrutia R, Ellenrieder V. Baumgart S, et al. Among authors: brunner m. Cancer Discov. 2014 Jun;4(6):688-701. doi: 10.1158/2159-8290.CD-13-0593. Epub 2014 Apr 2. Cancer Discov. 2014. PMID: 24694735 Free PMC article.
Effectiveness of fourth-line dual immunotherapy in hepatocellular carcinoma with simultaneous steroid administration for immune-related hepatitis.
Lowes K, Reinecke J, Brunner M, Scholz M, Kitz J, Michels B, Mekolli A, Gaedcke J, Seif Amir Hosseini A, Ströbel P, Ghadimi M, Ellenrieder V, Koenig A, Koenig U. Lowes K, et al. Among authors: brunner m. Therap Adv Gastroenterol. 2022 Feb 10;15:17562848211051026. doi: 10.1177/17562848211051026. eCollection 2022. Therap Adv Gastroenterol. 2022. PMID: 35178123 Free PMC article.
Cure Is Possible: Extensively Metastatic HER2-Positive Gastric Carcinoma with 5 years of Complete Remission after Therapy with the FLOT Regimen and Trastuzumab.
Schade S, Koenig U, Mekolli A, Gaedcke J, Neesse A, Reinecke J, Brunner M, Amir Hosseini AS, Kitz J, Stroebel P, Lotz J, Ghadimi M, Ellenrieder V, Koenig A. Schade S, et al. Among authors: brunner m. Case Rep Gastroenterol. 2022 Feb 17;16(1):80-88. doi: 10.1159/000520057. eCollection 2022 Jan-Apr. Case Rep Gastroenterol. 2022. PMID: 35350679 Free PMC article.
987 results