Bryan PN - Search Results

1

Engineering substrate preference in subtilisin: structural and kinetic analysis of a specificity mutant.

Ruan B, London V, Fisher KE, Gallagher DT, Bryan PN. Ruan B, et al. Among authors: bryan pn. Biochemistry. 2008 Jun 24;47(25):6628-36. doi: 10.1021/bi800089f. Biochemistry. 2008. PMID: 18507395

2

Sequence-specific 1H NMR assignments and secondary structure of the streptococcal protein G B2-domain.

Orban J, Alexander P, Bryan P. Orban J, et al. Biochemistry. 1992 Apr 14;31(14):3604-11. doi: 10.1021/bi00129a008. Biochemistry. 1992. PMID: 1314644

3

Kinetic analysis of folding and unfolding the 56 amino acid IgG-binding domain of streptococcal protein G.

Alexander P, Orban J, Bryan P. Alexander P, et al. Biochemistry. 1992 Aug 18;31(32):7243-8. doi: 10.1021/bi00147a006. Biochemistry. 1992. PMID: 1510916

4

Thermodynamic analysis of the folding of the streptococcal protein G IgG-binding domains B1 and B2: why small proteins tend to have high denaturation temperatures.

Alexander P, Fahnestock S, Lee T, Orban J, Bryan P. Alexander P, et al. Biochemistry. 1992 Apr 14;31(14):3597-603. doi: 10.1021/bi00129a007. Biochemistry. 1992. PMID: 1567818

5

Energetics of folding subtilisin BPN'.

Bryan P, Alexander P, Strausberg S, Schwarz F, Lan W, Gilliland G, Gallagher DT. Bryan P, et al. Biochemistry. 1992 Jun 2;31(21):4937-45. doi: 10.1021/bi00136a003. Biochemistry. 1992. PMID: 1599918

6

Large increases in general stability for subtilisin BPN' through incremental changes in the free energy of unfolding.

Pantoliano MW, Whitlow M, Wood JF, Dodd SW, Hardman KD, Rollence ML, Bryan PN. Pantoliano MW, et al. Among authors: bryan pn. Biochemistry. 1989 Sep 5;28(18):7205-13. doi: 10.1021/bi00444a012. Biochemistry. 1989. PMID: 2684274

7

The engineering of binding affinity at metal ion binding sites for the stabilization of proteins: subtilisin as a test case.

Pantoliano MW, Whitlow M, Wood JF, Rollence ML, Finzel BC, Gilliland GL, Poulos TL, Bryan PN. Pantoliano MW, et al. Among authors: bryan pn. Biochemistry. 1988 Nov 1;27(22):8311-7. doi: 10.1021/bi00422a004. Biochemistry. 1988. PMID: 3072018

8

Engineering thermostability in subtilisin BPN' by in vitro mutagenesis.

Rollence ML, Filpula D, Pantoliano MW, Bryan PN. Rollence ML, et al. Among authors: bryan pn. Crit Rev Biotechnol. 1988;8(3):217-24. doi: 10.3109/07388558809147558. Crit Rev Biotechnol. 1988. PMID: 3145814

9

Proteases of enhanced stability: characterization of a thermostable variant of subtilisin.

Bryan PN, Rollence ML, Pantoliano MW, Wood J, Finzel BC, Gilliland GL, Howard AJ, Poulos TL. Bryan PN, et al. Proteins. 1986 Dec;1(4):326-34. doi: 10.1002/prot.340010406. Proteins. 1986. PMID: 3329733

10

Protein engineering of subtilisin BPN': enhanced stabilization through the introduction of two cysteines to form a disulfide bond.

Pantoliano MW, Ladner RC, Bryan PN, Rollence ML, Wood JF, Poulos TL. Pantoliano MW, et al. Among authors: bryan pn. Biochemistry. 1987 Apr 21;26(8):2077-82. doi: 10.1021/bi00382a002. Biochemistry. 1987. PMID: 3476160

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