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Partial MHC class II constructs inhibit MIF/CD74 binding and downstream effects.
Benedek G, Meza-Romero R, Andrew S, Leng L, Burrows GG, Bourdette D, Offner H, Bucala R, Vandenbark AA. Benedek G, et al. Among authors: bucala r. Eur J Immunol. 2013 May;43(5):1309-21. doi: 10.1002/eji.201243162. Epub 2013 Apr 10. Eur J Immunol. 2013. PMID: 23576302 Free PMC article.
Predicted structure of MIF/CD74 and RTL1000/CD74 complexes.
Meza-Romero R, Benedek G, Leng L, Bucala R, Vandenbark AA. Meza-Romero R, et al. Among authors: bucala r. Metab Brain Dis. 2016 Apr;31(2):249-55. doi: 10.1007/s11011-016-9798-x. Epub 2016 Feb 6. Metab Brain Dis. 2016. PMID: 26851955 Free PMC article.
MIF and D-DT are potential disease severity modifiers in male MS subjects.
Benedek G, Meza-Romero R, Jordan K, Zhang Y, Nguyen H, Kent G, Li J, Siu E, Frazer J, Piecychna M, Du X, Sreih A, Leng L, Wiedrick J, Caillier SJ, Offner H, Oksenberg JR, Yadav V, Bourdette D, Bucala R, Vandenbark AA. Benedek G, et al. Among authors: bucala r. Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):E8421-E8429. doi: 10.1073/pnas.1712288114. Epub 2017 Sep 18. Proc Natl Acad Sci U S A. 2017. PMID: 28923927 Free PMC article.
A role for the B-cell CD74/macrophage migration inhibitory factor pathway in the immunomodulation of systemic lupus erythematosus by a therapeutic tolerogenic peptide.
Lapter S, Ben-David H, Sharabi A, Zinger H, Telerman A, Gordin M, Leng L, Bucala R, Shachar I, Mozes E. Lapter S, et al. Among authors: bucala r. Immunology. 2011 Jan;132(1):87-95. doi: 10.1111/j.1365-2567.2010.03342.x. Epub 2010 Aug 25. Immunology. 2011. PMID: 20738420 Free PMC article.
609 results