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A collapsed non-native RNA folding state.
Buchmueller KL, Webb AE, Richardson DA, Weeks KM. Buchmueller KL, et al. Nat Struct Biol. 2000 May;7(5):362-6. doi: 10.1038/75125. Nat Struct Biol. 2000. PMID: 10802730
Tris-borate is a poor counterion for RNA: a cautionary tale for RNA folding studies.
Buchmueller KL, Weeks KM. Buchmueller KL, et al. Nucleic Acids Res. 2004 Dec 15;32(22):e184. doi: 10.1093/nar/gnh182. Nucleic Acids Res. 2004. PMID: 15601995 Free PMC article.
Near native structure in an RNA collapsed state.
Buchmueller KL, Weeks KM. Buchmueller KL, et al. Biochemistry. 2003 Dec 2;42(47):13869-78. doi: 10.1021/bi035476k. Biochemistry. 2003. PMID: 14636054
Targeting the inverted CCAAT box 2 in the topoisomerase IIalpha promoter by JH-37, an imidazole-pyrrole polyamide hairpin: design, synthesis, molecular biology, and biophysical studies.
Henry JA, Le NM, Nguyen B, Howard CM, Bailey SL, Horick SM, Buchmueller KL, Kotecha M, Hochhauser D, Hartley JA, Wilson WD, Lee M. Henry JA, et al. Among authors: buchmueller kl. Biochemistry. 2004 Sep 28;43(38):12249-57. doi: 10.1021/bi048785z. Biochemistry. 2004. PMID: 15379563
Physical and structural basis for the strong interactions of the -ImPy- central pairing motif in the polyamide f-ImPyIm.
Buchmueller KL, Bailey SL, Matthews DA, Taherbhai ZT, Register JK, Davis ZS, Bruce CD, O'Hare C, Hartley JA, Lee M. Buchmueller KL, et al. Biochemistry. 2006 Nov 14;45(45):13551-65. doi: 10.1021/bi061245c. Biochemistry. 2006. PMID: 17087509
Molecular basis for the inhibition of HMGA1 proteins by distamycin A.
Smith AE, Buchmueller KL. Smith AE, et al. Among authors: buchmueller kl. Biochemistry. 2011 Sep 27;50(38):8107-16. doi: 10.1021/bi200822c. Epub 2011 Aug 30. Biochemistry. 2011. PMID: 21854010
Molecular recognition of DNA base pairs by the formamido/pyrrole and formamido/imidazole pairings in stacked polyamides.
Buchmueller KL, Staples AM, Uthe PB, Howard CM, Pacheco KA, Cox KK, Henry JA, Bailey SL, Horick SM, Nguyen B, Wilson WD, Lee M. Buchmueller KL, et al. Nucleic Acids Res. 2005 Feb 9;33(3):912-21. doi: 10.1093/nar/gki238. Print 2005. Nucleic Acids Res. 2005. PMID: 15703305 Free PMC article.
Synthesis and biophysical evaluation of minor-groove binding C-terminus modified pyrrole and imidazole triamide analogs of distamycin.
Brown T, Taherbhai Z, Sexton J, Sutterfield A, Turlington M, Jones J, Stallings L, Stewart M, Buchmueller K, Mackay H, O'hare C, Kluza J, Nguyen B, Wilson D, Lee M, Hartley JA. Brown T, et al. Bioorg Med Chem. 2007 Jan 1;15(1):474-83. doi: 10.1016/j.bmc.2006.09.037. Epub 2006 Oct 10. Bioorg Med Chem. 2007. PMID: 17035029
Extending the language of DNA molecular recognition by polyamides: unexpected influence of imidazole and pyrrole arrangement on binding affinity and specificity.
Buchmueller KL, Staples AM, Howard CM, Horick SM, Uthe PB, Le NM, Cox KK, Nguyen B, Pacheco KA, Wilson WD, Lee M. Buchmueller KL, et al. J Am Chem Soc. 2005 Jan 19;127(2):742-50. doi: 10.1021/ja044359p. J Am Chem Soc. 2005. PMID: 15643900
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