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44 results

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Page 1
Empirical treatment with valganciclovir in infants living with HIV and hospitalised with severe pneumonia in Africa: a multicentre, open-label, factorial, randomised, controlled, superiority trial.
Moraleda C, Tagarro A, Domínguez-Rodríguez S, Musiime V, Mujuru H, Chabala C, Mvalo T, Iroh-Tam PY, Bramugy J, Madrid L, Sacarlal J, Passanduca A, Sidat M, Cassia U, Aanyu HT, Tagoola A, Mutata C, Nduna B, Chawinga C, Ghambi L, Bates M, Fernández-Luis S, Seni A, Gafur M, Nalwanga D, Nansera D, Bwakura-Dangarembizi M, Namuziya N, Egbe FN, Tembo J, Ballesteros Á, Moh R, Manukyan L, Lora D, Marcy O, Jacobs TG, Burger D, Bassat Q, Leroy V, Nardone A, Buck WC, Rojo P; Empirical Clinical Trial Group. Moraleda C, et al. Among authors: buck wc. Lancet. 2026 Jul 17:S0140-6736(26)00754-3. doi: 10.1016/S0140-6736(26)00754-3. Online ahead of print. Lancet. 2026. PMID: 42468541 Free article.
Point-of-care early infant HIV diagnosis at birth in a pragmatic cluster-randomized trial in Mozambique and Tanzania: A comparative cost and cost-effectiveness study.
Elsbernd K, Sabi I, Jani IV, Mudenyanga C, Boniface S, Mahumane A, Lequechane J, Chale F, Meggi B, Pereira K, Edom R, Lwilla AF, Buck WC, Ntinyinya NE, Hoelscher M, Baernighausen T, Kroidl A, Kohler S; LIFE Study Consortium. Elsbernd K, et al. Among authors: buck wc. PLoS Med. 2026 May 6;23(5):e1005069. doi: 10.1371/journal.pmed.1005069. eCollection 2026 May. PLoS Med. 2026. PMID: 42090430 Free PMC article. Clinical Trial.
Pharmacokinetics and pharmacodynamics of valganciclovir in infants with severe HIV-associated pneumonia in Africa: a sub-study of the EMPIRICAL randomised controlled trial.
Jacobs TG, Mumbiro V, Tembo J, Egbe FN, Moraleda C, Beca LSDAB, Passanduca A, Kakooza L, Chitsamatanga M, Nduna B, Bramugy J, Tagarro A, Chhaganlal KD, Mutesi S, Mark NL, Bwakura-Dangarembizi M, Namuzizya N, Ballesteros A, Dominguez-Rodríguez S, Colbers A, Sacarlal J, Nalwanga D, Mujuru HA, Chabala C, Madrid L, Buck WC, Musiime V, Bates M, Rojo P, Burger DM; EMPIRICAL Clinical Trial Group. Jacobs TG, et al. Among authors: buck wc. EClinicalMedicine. 2026 Apr 13;94:103899. doi: 10.1016/j.eclinm.2026.103899. eCollection 2026 Apr. EClinicalMedicine. 2026. PMID: 42016921 Free PMC article.
Performance of an artificial intelligence algorithm for interpreting lung sounds from children hospitalised with pneumonia in Malawi.
Hoekstra NE, Chagomerana MB, Smith ZH, Kala A, McLane I, Verwey C, Olson D, Buck WC, Mulindwa J, Gaudio A, Kapoor S, Schuh HB, Chiume M, Fitzgerald E, Elhilali M, Mvalo T, Hosseinipour M, McCollum ED. Hoekstra NE, et al. Among authors: buck wc. J Glob Health. 2025 Sep 19;15:04264. doi: 10.7189/jogh.15.04264. J Glob Health. 2025. PMID: 40968644 Free PMC article.
Impact of point-of-care maternal viral load testing at delivery on vertical HIV transmission risk assessment and neonatal prophylaxis: a cluster randomized trial.
Lwilla AF, Elsbernd K, Boniface S, Edom R, Mahumane A, Meggi B, Buck WC, Lequechane J, Pereira K, Chiwerengo N, Chale F, Mudenyanga C, Mutsaka D, Mueller M, Ntinginya NE, Taveira N, Hoelscher M, Jani I, Kroidl A, Sabi I; and the LIFE Study Consortium. Lwilla AF, et al. Among authors: buck wc. J Int AIDS Soc. 2025 Aug;28(8):e70021. doi: 10.1002/jia2.70021. J Int AIDS Soc. 2025. PMID: 40719344 Free PMC article. Clinical Trial.
Non-invasive meningitis screening in neonates and infants: multicentre international study.
Ajanovic S, Jobst B, Jiménez J, Quesada R, Santos F, Carandell F, Lopez-Azorín M, Valverde E, Ybarra M, Bravo MC, Petrone P, Sial H, Muñoz D, Agut T, Salas B, Carreras N, Alarcón A, Iriondo M, Luaces C, Sidat M, Zandamela M, Rodrigues P, Graça D, Ngovene S, Bramugy J, Cossa A, Mucasse C, Buck WC, Arias S, El Abbass C, Tligi H, Barkat A, Ibáñez A, Parrilla M, Elvira L, Calvo C, Pellicer A, Cabañas F, Bassat Q; UNITED study group. Ajanovic S, et al. Among authors: buck wc. Pediatr Res. 2026 Feb;99(3):1040-1050. doi: 10.1038/s41390-025-04179-7. Epub 2025 Jul 23. Pediatr Res. 2026. PMID: 40702208 Free PMC article.
Statistical analysis plan for the "empirical treatment against cytomegalovirus and tuberculosis in HIV-infected infants with severe pneumonia" clinical trial.
Domínguez-Rodríguez S, Lora D, Tagarro A, Moraleda C, Ballesteros Á, Madrid L, Manukyan L, Marcy O, Leroy V, Nardone A, Burger D, Bassat Q, Bates M, Moh R, Tam PI, Mvalo T, Magallhaes J, Buck WC, Sacarlal J, Mussime V, Chabala C, Mujuru HA, Rojo P; EMPIRICAL group. Domínguez-Rodríguez S, et al. Among authors: buck wc. Trials. 2025 Apr 30;26(1):144. doi: 10.1186/s13063-025-08841-7. Trials. 2025. PMID: 40307889 Free PMC article.
Impact of Point-of-Care Birth Test-and-Treat on Clinical Outcomes Among Infants With HIV: A Cluster-Randomized Trial in Mozambique and Tanzania.
Jani IV, Sabi I, Elsbernd K, Meggi B, Mahumane A, Lwilla AF, Pereira K, Boniface S, Edom R, Lequechane J, Chale F, Chiwerengo N, Ntinginya NE, Mudenyanga C, Mueller M, Rauscher M, Hoelscher M, Taveira N, Buck WC, Kroidl A; LIFE Study Consortium. Jani IV, et al. Among authors: buck wc. Clin Infect Dis. 2025 Jun 4;80(5):1114-1124. doi: 10.1093/cid/ciae530. Clin Infect Dis. 2025. PMID: 39514367 Free PMC article. Clinical Trial.
44 results