Buckley AM - Search Results

1

Pyrazinib (P3), [(E)-2-(2-Pyrazin-2-yl-vinyl)-phenol], a small molecule pyrazine compound enhances radiosensitivity in oesophageal adenocarcinoma.

Buckley AM, Dunne MR, Lynam-Lennon N, Kennedy SA, Cannon A, Reynolds AL, Maher SG, Reynolds JV, Kennedy BN, O'Sullivan J. Buckley AM, et al. Cancer Lett. 2019 Apr 10;447:115-129. doi: 10.1016/j.canlet.2019.01.009. Epub 2019 Jan 19. Cancer Lett. 2019. PMID: 30664962

2

Proteomic signatures of radioresistance: Alteration of inflammation, angiogenesis and metabolism-related factors in radioresistant oesophageal adenocarcinoma.

Marcone S, Buckley A, Ryan CJ, McCabe M, Lynam-Lennon N, Matallanas D, O Sullivan J, Kennedy S. Marcone S, et al. Cancer Treat Res Commun. 2021;27:100376. doi: 10.1016/j.ctarc.2021.100376. Epub 2021 Apr 18. Cancer Treat Res Commun. 2021. PMID: 33882379 Free article.

3

Targeting hallmarks of cancer to enhance radiosensitivity in gastrointestinal cancers.

Buckley AM, Lynam-Lennon N, O'Neill H, O'Sullivan J. Buckley AM, et al. Nat Rev Gastroenterol Hepatol. 2020 May;17(5):298-313. doi: 10.1038/s41575-019-0247-2. Epub 2020 Jan 31. Nat Rev Gastroenterol Hepatol. 2020. PMID: 32005946 Review.

4

Real-time metabolic profiling of oesophageal tumours reveals an altered metabolic phenotype to different oxygen tensions and to treatment with Pyrazinib.

Buckley AM, Dunne MR, Morrissey ME, Kennedy SA, Nolan A, Davern M, Foley EK, Clarke N, Lysaght J, Ravi N, O'Toole D, MacCarthy F, Reynolds JV, Kennedy BN, O'Sullivan J. Buckley AM, et al. Sci Rep. 2020 Jul 21;10(1):12105. doi: 10.1038/s41598-020-68777-7. Sci Rep. 2020. PMID: 32694701 Free PMC article.

5

Combining 1,4-dihydroxy quininib with Bevacizumab/FOLFOX alters angiogenic and inflammatory secretions in ex vivo colorectal tumors.

Kennedy SA, Morrissey ME, Dunne MR, O'Connell F, Butler CT, Cathcart MC, Buckley AM, Mehigan BJ, Larkin JO, McCormick P, Kennedy BN, O'Sullivan J. Kennedy SA, et al. Among authors: buckley am. BMC Cancer. 2020 Oct 2;20(1):952. doi: 10.1186/s12885-020-07430-y. BMC Cancer. 2020. PMID: 33008336 Free PMC article.

6

1,4-dihydroxy quininib attenuates growth of colorectal cancer cells and xenografts and regulates the TIE-2 signaling pathway in patient tumours.

Butler CT, Kennedy SA, Buckley A, Doyle R, Conroy E, Gallagher WM, O'Sullivan J, Kennedy BN. Butler CT, et al. Oncotarget. 2019 Jun 4;10(38):3725-3744. doi: 10.18632/oncotarget.26966. eCollection 2019 Jun 4. Oncotarget. 2019. PMID: 31217905 Free PMC article.

7

Leukaemia inhibitory factor is associated with treatment resistance in oesophageal adenocarcinoma.

Buckley AM, Lynam-Lennon N, Kennedy SA, Dunne MR, Aird JJ, Foley EK, Clarke N, Ravi N, O'Toole D, Reynolds JV, Kennedy BN, O'Sullivan J. Buckley AM, et al. Oncotarget. 2018 Sep 14;9(72):33634-33647. doi: 10.18632/oncotarget.25950. eCollection 2018 Sep 14. Oncotarget. 2018. PMID: 30263091 Free PMC article.

8

Characterisation of an Isogenic Model of Cisplatin Resistance in Oesophageal Adenocarcinoma Cells.

Buckley AM, Bibby BA, Dunne MR, Kennedy SA, Davern MB, Kennedy BN, Maher SG, O'Sullivan J. Buckley AM, et al. Pharmaceuticals (Basel). 2019 Feb 20;12(1):33. doi: 10.3390/ph12010033. Pharmaceuticals (Basel). 2019. PMID: 30791601 Free PMC article.

9

Opposing Immune-Metabolic Signature in Visceral Versus Subcutaneous Adipose Tissue in Patients with Adenocarcinoma of the Oesophagus and the Oesophagogastric Junction.

Heeran AB, McCready J, Dunne MR, Donlon NE, Nugent TS, Bhardwaj A, Mitchelson KAJ, Buckley AM, Ravi N, Roche HM, Reynolds JV, Lynam-Lennon N, O'Sullivan J. Heeran AB, et al. Among authors: buckley am. Metabolites. 2021 Nov 10;11(11):768. doi: 10.3390/metabo11110768. Metabolites. 2021. PMID: 34822426 Free PMC article.

10

Radiation-induced Bystander Effect (RIBE) alters mitochondrial metabolism using a human rectal cancer ex vivo explant model.

Heeran AB, Berrigan HP, Buckley CE, Bottu HM, Prendiville O, Buckley AM, Clarke N, Donlon NE, Nugent TS, Durand M, Dunne C, Larkin JO, Mehigan B, McCormick P, Brennan L, Lynam-Lennon N, O'Sullivan J. Heeran AB, et al. Among authors: buckley am, buckley ce. Transl Oncol. 2021 Jan;14(1):100882. doi: 10.1016/j.tranon.2020.100882. Epub 2020 Oct 23. Transl Oncol. 2021. PMID: 33129115 Free PMC article.

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