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New Class of Antitrypanosomal Agents Based on Imidazopyridines.
Silva DG, Gillespie JR, Ranade RM, Herbst ZM, Nguyen UTT, Buckner FS, Montanari CA, Gelb MH. Silva DG, et al. Among authors: buckner fs. ACS Med Chem Lett. 2017 Jun 27;8(7):766-770. doi: 10.1021/acsmedchemlett.7b00202. eCollection 2017 Jul 13. ACS Med Chem Lett. 2017. PMID: 28740614 Free PMC article.
Glycogen synthase kinase 3 is a potential drug target for African trypanosomiasis therapy.
Ojo KK, Gillespie JR, Riechers AJ, Napuli AJ, Verlinde CL, Buckner FS, Gelb MH, Domostoj MM, Wells SJ, Scheer A, Wells TN, Van Voorhis WC. Ojo KK, et al. Among authors: buckner fs. Antimicrob Agents Chemother. 2008 Oct;52(10):3710-7. doi: 10.1128/AAC.00364-08. Epub 2008 Jul 21. Antimicrob Agents Chemother. 2008. PMID: 18644955 Free PMC article.
A binding hotspot in Trypanosoma cruzi histidyl-tRNA synthetase revealed by fragment-based crystallographic cocktail screens.
Koh CY, Siddaramaiah LK, Ranade RM, Nguyen J, Jian T, Zhang Z, Gillespie JR, Buckner FS, Verlinde CL, Fan E, Hol WG. Koh CY, et al. Among authors: buckner fs. Acta Crystallogr D Biol Crystallogr. 2015 Aug;71(Pt 8):1684-98. doi: 10.1107/S1399004715007683. Epub 2015 Jul 31. Acta Crystallogr D Biol Crystallogr. 2015. PMID: 26249349 Free PMC article.
Characterization of Trypanosoma brucei dihydroorotate dehydrogenase as a possible drug target; structural, kinetic and RNAi studies.
Arakaki TL, Buckner FS, Gillespie JR, Malmquist NA, Phillips MA, Kalyuzhniy O, Luft JR, Detitta GT, Verlinde CL, Van Voorhis WC, Hol WG, Merritt EA. Arakaki TL, et al. Among authors: buckner fs. Mol Microbiol. 2008 Apr;68(1):37-50. doi: 10.1111/j.1365-2958.2008.06131.x. Epub 2008 Feb 26. Mol Microbiol. 2008. PMID: 18312275 Free PMC article.
Substituted 2-phenylimidazopyridines: a new class of drug leads for human African trypanosomiasis.
Tatipaka HB, Gillespie JR, Chatterjee AK, Norcross NR, Hulverson MA, Ranade RM, Nagendar P, Creason SA, McQueen J, Duster NA, Nagle A, Supek F, Molteni V, Wenzler T, Brun R, Glynne R, Buckner FS, Gelb MH. Tatipaka HB, et al. Among authors: buckner fs. J Med Chem. 2014 Feb 13;57(3):828-35. doi: 10.1021/jm401178t. Epub 2014 Jan 15. J Med Chem. 2014. PMID: 24354316 Free PMC article.
140 results