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Optimization of Drug Candidates That Inhibit the D-Loop Activity of RAD51.
Budke B, Tueckmantel W, Miles K, Kozikowski AP, Connell PP. Budke B, et al. ChemMedChem. 2019 May 17;14(10):1031-1040. doi: 10.1002/cmdc.201900075. Epub 2019 Apr 17. ChemMedChem. 2019. PMID: 30957434 Free PMC article.
RAD54 family translocases counter genotoxic effects of RAD51 in human tumor cells.
Mason JM, Dusad K, Wright WD, Grubb J, Budke B, Heyer WD, Connell PP, Weichselbaum RR, Bishop DK. Mason JM, et al. Among authors: Budke B. Nucleic Acids Res. 2015 Mar 31;43(6):3180-96. doi: 10.1093/nar/gkv175. Epub 2015 Mar 12. Nucleic Acids Res. 2015. PMID: 25765654 Free PMC article.
RI-1: a chemical inhibitor of RAD51 that disrupts homologous recombination in human cells.
Budke B, Logan HL, Kalin JH, Zelivianskaia AS, Cameron McGuire W, Miller LL, Stark JM, Kozikowski AP, Bishop DK, Connell PP. Budke B, et al. Nucleic Acids Res. 2012 Aug;40(15):7347-57. doi: 10.1093/nar/gks353. Epub 2012 May 9. Nucleic Acids Res. 2012. PMID: 22573178 Free PMC article.
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