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Buparlisib is a brain penetrable pan-PI3K inhibitor.
de Gooijer MC, Zhang P, Buil LCM, Çitirikkaya CH, Thota N, Beijnen JH, van Tellingen O. de Gooijer MC, et al. Among authors: buil lcm. Sci Rep. 2018 Jul 17;8(1):10784. doi: 10.1038/s41598-018-29062-w. Sci Rep. 2018. PMID: 30018387 Free PMC article.
MELK Inhibition in Diffuse Intrinsic Pontine Glioma.
Meel MH, de Gooijer MC, Guillén Navarro M, Waranecki P, Breur M, Buil LCM, Wedekind LE, Twisk JWR, Koster J, Hashizume R, Raabe EH, Montero Carcaboso A, Bugiani M, van Tellingen O, van Vuurden DG, Kaspers GJL, Hulleman E. Meel MH, et al. Among authors: buil lcm. Clin Cancer Res. 2018 Nov 15;24(22):5645-5657. doi: 10.1158/1078-0432.CCR-18-0924. Epub 2018 Jul 30. Clin Cancer Res. 2018. PMID: 30061363
ABCB1 Attenuates the Brain Penetration of the PARP Inhibitor AZD2461.
de Gooijer MC, Buil LCM, Çitirikkaya CH, Hermans J, Beijnen JH, van Tellingen O. de Gooijer MC, et al. Among authors: buil lcm. Mol Pharm. 2018 Nov 5;15(11):5236-5243. doi: 10.1021/acs.molpharmaceut.8b00742. Epub 2018 Oct 5. Mol Pharm. 2018. PMID: 30252484
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