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Burden of risk alleles for hypertension increases risk of intracerebral hemorrhage.
Falcone GJ, Biffi A, Devan WJ, Jagiella JM, Schmidt H, Kissela B, Hansen BM, Jimenez-Conde J, Giralt-Steinhauer E, Elosua R, Cuadrado-Godia E, Soriano C, Ayres AM, Schwab K, Pera J, Urbanik A, Rost NS, Goldstein JN, Viswanathan A, Pichler A, Enzinger C, Norrving B, Tirschwell DL, Selim M, Brown DL, Silliman SL, Worrall BB, Meschia JF, Kidwell CS, Montaner J, Fernandez-Cadenas I, Delgado P, Broderick JP, Greenberg SM, Roquer J, Lindgren A, Slowik A, Schmidt R, Flaherty ML, Kleindorfer DO, Langefeld CD, Woo D, Rosand J; International Stroke Genetics Consortium. Falcone GJ, et al. Stroke. 2012 Nov;43(11):2877-83. doi: 10.1161/STROKEAHA.112.659755. Epub 2012 Aug 28. Stroke. 2012. PMID: 22933587 Free PMC article.
BACKGROUND AND PURPOSE: Genetic variation influences risk of intracerebral hemorrhage (ICH). Hypertension (HTN) is a potent risk factor for ICH and several common genetic variants (single nucleotide polymorphisms [SNPs]) associated with b …
BACKGROUND AND PURPOSE: Genetic variation influences risk of intracerebral hemorrhage (ICH). Hypertension …
Ethnic and Racial Variation in Intracerebral Hemorrhage Risk Factors and Risk Factor Burden.
Kittner SJ, Sekar P, Comeau ME, Anderson CD, Parikh GY, Tavarez T, Flaherty ML, Testai FD, Frankel MR, James ML, Sung G, Elkind MSV, Worrall BB, Kidwell CS, Gonzales NR, Koch S, Hall CE, Birnbaum L, Mayson D, Coull B, Malkoff MD, Sheth KN, McCauley JL, Osborne J, Morgan M, Gilkerson LA, Behymer TP, Demel SL, Moomaw CJ, Rosand J, Langefeld CD, Woo D. Kittner SJ, et al. JAMA Netw Open. 2021 Aug 2;4(8):e2121921. doi: 10.1001/jamanetworkopen.2021.21921. JAMA Netw Open. 2021. PMID: 34424302 Free PMC article.
IMPORTANCE: Black and Hispanic individuals have an increased risk of intracerebral hemorrhage (ICH) compared with their White counterparts, but no large studies of ICH have been conducted in these disproportionately affected populations. ...DESI …
IMPORTANCE: Black and Hispanic individuals have an increased risk of intracerebral hemorrhage (ICH) compa …
Burden of blood pressure-related alleles is associated with larger hematoma volume and worse outcome in intracerebral hemorrhage.
Falcone GJ, Biffi A, Devan WJ, Brouwers HB, Anderson CD, Valant V, Ayres AM, Schwab K, Rost NS, Goldstein JN, Viswanathan A, Greenberg SM, Selim M, Meschia JF, Brown DL, Worrall BB, Silliman SL, Tirschwell DL, Rosand J; GOCHA Investigators. Falcone GJ, et al. Stroke. 2013 Feb;44(2):321-6. doi: 10.1161/STROKEAHA.112.675181. Epub 2013 Jan 15. Stroke. 2013. PMID: 23321443 Free PMC article.
BACKGROUND AND PURPOSE: Intracerebral hemorrhage (ICH) is the acute manifestation of a progressive disease of the cerebral small vessels. The severity of this disease seems to influence not only risk of ICH but also the size of the hematoma. As …
BACKGROUND AND PURPOSE: Intracerebral hemorrhage (ICH) is the acute manifestation of a progressive disease of the cerebral …
Cerebral microbleeds: a review of clinical, genetic, and neuroimaging associations.
Yates PA, Villemagne VL, Ellis KA, Desmond PM, Masters CL, Rowe CC. Yates PA, et al. Front Neurol. 2014 Jan 6;4:205. doi: 10.3389/fneur.2013.00205. eCollection 2014 Jan 6. Front Neurol. 2014. PMID: 24432010 Free PMC article. Review.
Other neuroimaging findings that have been linked with microbleeds include lacunar infarcts and white matter hyperintensities on MRI, and increased cerebral beta-amyloid burden using (11)C-PiB Positron Emission Tomography. The presence of microbleeds has been …
Other neuroimaging findings that have been linked with microbleeds include lacunar infarcts and white matter hyperintensities on MRI, and …