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Inferring rare disease risk variants based on exact probabilities of sharing by multiple affected relatives.
Bureau A, Younkin SG, Parker MM, Bailey-Wilson JE, Marazita ML, Murray JC, Mangold E, Albacha-Hejazi H, Beaty TH, Ruczinski I. Bureau A, et al. Bioinformatics. 2014 Aug 1;30(15):2189-96. doi: 10.1093/bioinformatics/btu198. Epub 2014 Apr 16. Bioinformatics. 2014. PMID: 24740360 Free PMC article.
MOTIVATION: Family-based designs are regaining popularity for genomic sequencing studies because they provide a way to test cosegregation with disease of variants that are too rare in the population to be tested individually in a conventional case-control study. ... …
MOTIVATION: Family-based designs are regaining popularity for genomic sequencing studies because they provide a way to test cosegrega …
A genome-wide association study of suicidal behavior.
Galfalvy H, Haghighi F, Hodgkinson C, Goldman D, Oquendo MA, Burke A, Huang YY, Giegling I, Rujescu D, Bureau A, Turecki G, Mann JJ. Galfalvy H, et al. Among authors: bureau a. Am J Med Genet B Neuropsychiatr Genet. 2015 Oct;168(7):557-63. doi: 10.1002/ajmg.b.32330. Epub 2015 Jun 16. Am J Med Genet B Neuropsychiatr Genet. 2015. PMID: 26079190
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