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DNA methyltransferase Dnmt1 associates with histone deacetylase activity.
Fuks F, Burgers WA, Brehm A, Hughes-Davies L, Kouzarides T. Fuks F, et al. Among authors: burgers wa. Nat Genet. 2000 Jan;24(1):88-91. doi: 10.1038/71750. Nat Genet. 2000. PMID: 10615135
Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription.
Fuks F, Burgers WA, Godin N, Kasai M, Kouzarides T. Fuks F, et al. Among authors: burgers wa. EMBO J. 2001 May 15;20(10):2536-44. doi: 10.1093/emboj/20.10.2536. EMBO J. 2001. PMID: 11350943 Free PMC article.
DNA methyltransferases get connected to chromatin.
Burgers WA, Fuks F, Kouzarides T. Burgers WA, et al. Trends Genet. 2002 Jun;18(6):275-7. doi: 10.1016/S0168-9525(02)02667-7. Trends Genet. 2002. PMID: 12044346
Dnmt3L is a transcriptional repressor that recruits histone deacetylase.
Deplus R, Brenner C, Burgers WA, Putmans P, Kouzarides T, de Launoit Y, Fuks F. Deplus R, et al. Among authors: burgers wa. Nucleic Acids Res. 2002 Sep 1;30(17):3831-8. doi: 10.1093/nar/gkf509. Nucleic Acids Res. 2002. PMID: 12202768 Free PMC article.
Viral oncoproteins target the DNA methyltransferases.
Burgers WA, Blanchon L, Pradhan S, de Launoit Y, Kouzarides T, Fuks F. Burgers WA, et al. Oncogene. 2007 Mar 8;26(11):1650-5. doi: 10.1038/sj.onc.1209950. Epub 2006 Sep 18. Oncogene. 2007. PMID: 16983344 Free PMC article.
Construction, characterization, and immunogenicity of a multigene modified vaccinia Ankara (MVA) vaccine based on HIV type 1 subtype C.
Burgers WA, Shephard E, Monroe JE, Greenhalgh T, Binder A, Hurter E, Van Harmelen JH, Williamson C, Williamson AL. Burgers WA, et al. AIDS Res Hum Retroviruses. 2008 Feb;24(2):195-206. doi: 10.1089/aid.2007.0205. AIDS Res Hum Retroviruses. 2008. PMID: 18240957
A multigene HIV type 1 subtype C modified vaccinia Ankara (MVA) vaccine efficiently boosts immune responses to a DNA vaccine in mice.
Shephard E, Burgers WA, Van Harmelen JH, Monroe JE, Greenhalgh T, Williamson C, Williamson AL. Shephard E, et al. Among authors: burgers wa. AIDS Res Hum Retroviruses. 2008 Feb;24(2):207-17. doi: 10.1089/aid.2007.0206. AIDS Res Hum Retroviruses. 2008. PMID: 18240963
HIV Skews the Lineage-Defining Transcriptional Profile of Mycobacterium tuberculosis-Specific CD4+ T Cells.
Riou C, Strickland N, Soares AP, Corleis B, Kwon DS, Wherry EJ, Wilkinson RJ, Burgers WA. Riou C, et al. Among authors: burgers wa. J Immunol. 2016 Apr 1;196(7):3006-18. doi: 10.4049/jimmunol.1502094. Epub 2016 Feb 29. J Immunol. 2016. PMID: 26927799 Free PMC article.
HIV-specific T-cell responses detected in the genital tract of chronically HIV-infected women are largely monofunctional.
Bere A, Denny L, Naicker P, Burgers WA, Passmore JA. Bere A, et al. Among authors: burgers wa. Immunology. 2013 Jul;139(3):342-51. doi: 10.1111/imm.12084. Immunology. 2013. PMID: 23374084 Free PMC article.
Design and preclinical evaluation of a multigene human immunodeficiency virus type 1 subtype C DNA vaccine for clinical trial.
Burgers WA, van Harmelen JH, Shephard E, Adams C, Mgwebi T, Bourn W, Hanke T, Williamson AL, Williamson C. Burgers WA, et al. J Gen Virol. 2006 Feb;87(Pt 2):399-410. doi: 10.1099/vir.0.81379-0. J Gen Virol. 2006. PMID: 16432028
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