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Sex is a major determinant of CYP3A4 expression in human liver.
Wolbold R, Klein K, Burk O, Nüssler AK, Neuhaus P, Eichelbaum M, Schwab M, Zanger UM. Wolbold R, et al. Among authors: burk o. Hepatology. 2003 Oct;38(4):978-88. doi: 10.1053/jhep.2003.50393. Hepatology. 2003. PMID: 14512885
Cytochrome P450 3A and their regulation.
Burk O, Wojnowski L. Burk O, et al. Naunyn Schmiedebergs Arch Pharmacol. 2004 Jan;369(1):105-24. doi: 10.1007/s00210-003-0815-3. Epub 2003 Oct 21. Naunyn Schmiedebergs Arch Pharmacol. 2004. PMID: 14569421 Review.
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