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The structural basis of camptothecin interactions with human serum albumin: impact on drug stability.
Burke TG, Mi Z. Burke TG, et al. J Med Chem. 1994 Jan 7;37(1):40-6. doi: 10.1021/jm00027a005. J Med Chem. 1994. PMID: 8289200
Degradation of camptothecin-20(S)-glycinate ester prodrug under physiological conditions.
Liu X, Zhang J, Song L, Lynn BC, Burke TG. Liu X, et al. Among authors: burke tg. J Pharm Biomed Anal. 2004 Sep 3;35(5):1113-25. doi: 10.1016/j.jpba.2004.04.006. J Pharm Biomed Anal. 2004. PMID: 15336358
Synthesis and evaluation of a novel E-ring modified alpha-hydroxy keto ether analogue of camptothecin.
Du W, Curran DP, Bevins RL, Zimmer SG, Zhang J, Burke TG. Du W, et al. Among authors: burke tg. Bioorg Med Chem. 2002 Jan;10(1):103-10. doi: 10.1016/s0968-0896(01)00252-8. Bioorg Med Chem. 2002. PMID: 11738612
Plasma and tissue disposition of non-liposomal DB-67 and liposomal DB-67 in C.B-17 SCID mice.
Zamboni WC, Jung LL, Strychor S, Joseph E, Zamboni BA, Fetterman SA, Sidone BJ, Burke TG, Curran DP, Eiseman JL. Zamboni WC, et al. Among authors: burke tg. Invest New Drugs. 2008 Oct;26(5):399-406. doi: 10.1007/s10637-007-9109-9. Epub 2008 Feb 2. Invest New Drugs. 2008. PMID: 18246299
The acidic microclimate in poly(lactide-co-glycolide) microspheres stabilizes camptothecins.
Shenderova A, Burke TG, Schwendeman SP. Shenderova A, et al. Among authors: burke tg. Pharm Res. 1999 Feb;16(2):241-8. doi: 10.1023/a:1018876308346. Pharm Res. 1999. PMID: 10100309
Stabilization of 10-hydroxycamptothecin in poly(lactide-co-glycolide) microsphere delivery vehicles.
Shenderova A, Burke TG, Schwendeman SP. Shenderova A, et al. Among authors: burke tg. Pharm Res. 1997 Oct;14(10):1406-14. doi: 10.1023/a:1012172722246. Pharm Res. 1997. PMID: 9358554
Fluorescence detection of the anticancer drug topotecan in plasma and whole blood by two-photon excitation.
Burke TG, Malak H, Gryczynski I, Mi Z, Lakowicz JR. Burke TG, et al. Anal Biochem. 1996 Nov 15;242(2):266-70. doi: 10.1006/abio.1996.0463. Anal Biochem. 1996. PMID: 8937572 Free PMC article.
Ethyl substitution at the 7 position extends the half-life of 10-hydroxycamptothecin in the presence of human serum albumin.
Burke TG, Mi Z. Burke TG, et al. J Med Chem. 1993 Aug 20;36(17):2580-2. doi: 10.1021/jm00069a020. J Med Chem. 1993. PMID: 8355258 No abstract available.
Preferential binding of the carboxylate form of camptothecin by human serum albumin.
Burke TG, Mi Z. Burke TG, et al. Anal Biochem. 1993 Jul;212(1):285-7. doi: 10.1006/abio.1993.1325. Anal Biochem. 1993. PMID: 8368506 No abstract available.
The highly lipophilic DNA topoisomerase I inhibitor DB-67 displays elevated lactone levels in human blood and potent anticancer activity.
Bom D, Curran DP, Zhang J, Zimmer SG, Bevins R, Kruszewski S, Howe JN, Bingcang A, Latus LJ, Burke TG. Bom D, et al. Among authors: burke tg. J Control Release. 2001 Jul 6;74(1-3):325-33. doi: 10.1016/s0168-3659(01)00343-1. J Control Release. 2001. PMID: 11489514
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