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Page 1
Endocrine-Exocrine Signaling Drives Obesity-Associated Pancreatic Ductal Adenocarcinoma.
Chung KM, Singh J, Lawres L, Dorans KJ, Garcia C, Burkhardt DB, Robbins R, Bhutkar A, Cardone R, Zhao X, Babic A, Vayrynen SA, Dias Costa A, Nowak JA, Chang DT, Dunne RF, Hezel AF, Koong AC, Wilhelm JJ, Bellin MD, Nylander V, Gloyn AL, McCarthy MI, Kibbey RG, Krishnaswamy S, Wolpin BM, Jacks T, Fuchs CS, Muzumdar MD. Chung KM, et al. Among authors: burkhardt db. Cell. 2020 May 14;181(4):832-847.e18. doi: 10.1016/j.cell.2020.03.062. Epub 2020 Apr 17. Cell. 2020. PMID: 32304665 Free PMC article.
Immune cells and their inflammatory mediators modify β cells and cause checkpoint inhibitor-induced diabetes.
Perdigoto AL, Deng S, Du KC, Kuchroo M, Burkhardt DB, Tong A, Israel G, Robert ME, Weisberg SP, Kirkiles-Smith N, Stamatouli AM, Kluger HM, Quandt Z, Young A, Yang ML, Mamula MJ, Pober JS, Anderson MS, Krishnaswamy S, Herold KC. Perdigoto AL, et al. Among authors: burkhardt db. JCI Insight. 2022 Sep 8;7(17):e156330. doi: 10.1172/jci.insight.156330. JCI Insight. 2022. PMID: 35925682 Free PMC article.
Multiscale PHATE identifies multimodal signatures of COVID-19.
Kuchroo M, Huang J, Wong P, Grenier JC, Shung D, Tong A, Lucas C, Klein J, Burkhardt DB, Gigante S, Godavarthi A, Rieck B, Israelow B, Simonov M, Mao T, Oh JE, Silva J, Takahashi T, Odio CD, Casanovas-Massana A, Fournier J; Yale IMPACT Team; Farhadian S, Dela Cruz CS, Ko AI, Hirn MJ, Wilson FP, Hussin JG, Wolf G, Iwasaki A, Krishnaswamy S. Kuchroo M, et al. Among authors: burkhardt db. Nat Biotechnol. 2022 May;40(5):681-691. doi: 10.1038/s41587-021-01186-x. Epub 2022 Feb 28. Nat Biotechnol. 2022. PMID: 35228707 Free PMC article.
Quantifying the effect of experimental perturbations at single-cell resolution.
Burkhardt DB, Stanley JS 3rd, Tong A, Perdigoto AL, Gigante SA, Herold KC, Wolf G, Giraldez AJ, van Dijk D, Krishnaswamy S. Burkhardt DB, et al. Nat Biotechnol. 2021 May;39(5):619-629. doi: 10.1038/s41587-020-00803-5. Epub 2021 Feb 8. Nat Biotechnol. 2021. PMID: 33558698 Free PMC article.
Visualizing structure and transitions in high-dimensional biological data.
Moon KR, van Dijk D, Wang Z, Gigante S, Burkhardt DB, Chen WS, Yim K, Elzen AVD, Hirn MJ, Coifman RR, Ivanova NB, Wolf G, Krishnaswamy S. Moon KR, et al. Among authors: burkhardt db. Nat Biotechnol. 2019 Dec;37(12):1482-1492. doi: 10.1038/s41587-019-0336-3. Epub 2019 Dec 3. Nat Biotechnol. 2019. PMID: 31796933 Free PMC article.
12 results