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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 1
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1951 3
1953 3
1954 1
1955 3
1956 1
1958 2
1959 2
1960 2
1961 3
1962 6
1963 15
1964 11
1965 12
1966 3
1967 10
1968 16
1969 14
1970 15
1971 21
1972 9
1973 22
1974 31
1975 12
1976 20
1977 14
1978 14
1979 32
1980 23
1981 14
1982 25
1983 22
1984 33
1985 32
1986 22
1987 28
1988 34
1989 28
1990 28
1991 25
1992 38
1993 19
1994 30
1995 34
1996 33
1997 32
1998 40
1999 37
2000 30
2001 44
2002 40
2003 30
2004 42
2005 52
2006 73
2007 91
2008 80
2009 76
2010 91
2011 84
2012 88
2013 99
2014 89
2015 90
2016 107
2017 109
2018 140
2019 157
2020 187
2021 154
2022 154
2023 194
2024 181
2025 190
2026 9

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3,275 results

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Page 1
Burn Debridement: Are We Optimizing Outcomes?
Bolton L. Bolton L. Wounds. 2019 Dec;31(12):298-300. Wounds. 2019. PMID: 31833838 Free article.
Early surgical debridement of nonviable tissue within 48 hours of burn injury is the standard of care (SOC) for burns extending into and beyond the deep dermis. Early debridement has been reported to reduce infection and complication rates, shorten hos …
Early surgical debridement of nonviable tissue within 48 hours of burn injury is the standard of care (SOC) for burns e …
Burn Wounds and Enzymatic Debridement (ED)-Past, Present, and Future.
Atiyeh B, Makkawi K, Beaineh P. Atiyeh B, et al. J Burn Care Res. 2024 Aug 6;45(4):864-876. doi: 10.1093/jbcr/irae059. J Burn Care Res. 2024. PMID: 38586910
INTRODUCTION: Excision of necrotic and devitalized tissues of deep burns is key for optimal care of burn injuries. However, the modality of early tangential excision followed by skin grafting proposed by Zora Janzekovic 5 decades ago was not received initially with …
INTRODUCTION: Excision of necrotic and devitalized tissues of deep burns is key for optimal care of burn injuries. However, th …
Rapid enzymatic burn debridement: A review of the paediatric clinical trial experience.
Shoham Y, Krieger Y, Rubin G, Koenigs I, Hartmann B, Sander F, Schulz A, David K, Rosenberg L, Silberstein E. Shoham Y, et al. Int Wound J. 2020 Oct;17(5):1337-1345. doi: 10.1111/iwj.13405. Epub 2020 May 22. Int Wound J. 2020. PMID: 32445271 Free PMC article. Review.
NexoBrid (NXB) has been proven to be an effective selective enzymatic debridement agent in adults. This manuscript presents the combined clinical trial experience with NXB in children. Hundred and ten children aged 0.5 to 18 years suffering from deep thermal burns o …
NexoBrid (NXB) has been proven to be an effective selective enzymatic debridement agent in adults. This manuscript presents the combi …
Selective debridement of burn wounds using hydrosurgery system.
Yuan M, Yin M, Zhang L, Feng J, Zhu J, Zhou Z, Shu B, Zhou F, Zhang F, Yin H, Wang X, Qi S, Wu J. Yuan M, et al. Int Wound J. 2020 Apr;17(2):300-309. doi: 10.1111/iwj.13270. Epub 2019 Nov 29. Int Wound J. 2020. PMID: 31782622 Free PMC article.
This study was designed to investigate the possible tissue selectivity of hydrosurgery in the debridement in burn wounds. Deep partial-thickness burns were produced on the back of porcine, and 48 hours later, both burn wounds and normal skin were de …
This study was designed to investigate the possible tissue selectivity of hydrosurgery in the debridement in burn wounds. Deep …
Bromelain-based enzymatic burn debridement: A systematic review of clinical studies on patient safety, efficacy and long-term outcomes.
Shoham Y, Gasteratos K, Singer AJ, Krieger Y, Silberstein E, Goverman J. Shoham Y, et al. Int Wound J. 2023 Dec;20(10):4364-4383. doi: 10.1111/iwj.14308. Epub 2023 Jul 16. Int Wound J. 2023. PMID: 37455553 Free PMC article.
In 2012 the European Medicines Agency approved a pineapple stem-derived Bromelain-based debridement concentrate of proteolytic enzymes (NexoBrid, MediWound Ltd, Yavne, Israel) for adult deep burns. ...The included studies report the positive effects of Nexobrid on …
In 2012 the European Medicines Agency approved a pineapple stem-derived Bromelain-based debridement concentrate of proteolytic enzyme …
Italian recommendations on enzymatic debridement in burn surgery.
Ranno R, Vestita M, Maggio G, Verrienti P, Melandri D, Orlandi C, Perniciaro G, De Angelis A, D'Alessio R, Mataro I, Pagnozzi E, Alessandro G, Caleffi E, Di Lonardo A, Ciappi S, Palombo P, Posadinu MA, Stella M, Romeo M, Minic J, Governa M, Giudice G. Ranno R, et al. Burns. 2021 Mar;47(2):408-416. doi: 10.1016/j.burns.2020.07.006. Epub 2020 Jul 15. Burns. 2021. PMID: 32723513 Free article.
METHODS: The Italian recommendations, endorsed by SIUST (Italian Society of Burn Surgery), on using enzymatic debridement to remove eschars for burn treatment were defined. ...DISCUSSION: The statements provided by the Italian consensus panel represent a "rea …
METHODS: The Italian recommendations, endorsed by SIUST (Italian Society of Burn Surgery), on using enzymatic debridement to r …
A systematic review on surgical and nonsurgical debridement techniques of burn wounds.
Kwa KAA, Goei H, Breederveld RS, Middelkoop E, van der Vlies CH, van Baar ME. Kwa KAA, et al. J Plast Reconstr Aesthet Surg. 2019 Nov;72(11):1752-1762. doi: 10.1016/j.bjps.2019.07.006. Epub 2019 Aug 7. J Plast Reconstr Aesthet Surg. 2019. PMID: 31515194
OBJECTIVE: To provide a complete overview of all burn debridement techniques studied in recent literature and to find the best evidence with regard to efficiency and safety. ...All studies published from 1990 onwards, on the efficiency and/or safety of burn …
OBJECTIVE: To provide a complete overview of all burn debridement techniques studied in recent literature and to find the best …
Enzymatic Debridement of Porcine Burn Wounds via a Novel Protease, SN514.
Stone R, Jockheck-Clark AR, Natesan S, Rizzo JA, Wienandt NA, Scott LL, Larson DA, Wall JT, Holik MA, Shaffer LJ, Park N, Jovanovic A, Tetens S, Roche ED, Shi L, Christy RJ. Stone R, et al. J Burn Care Res. 2020 Sep 23;41(5):1015-1028. doi: 10.1093/jbcr/iraa111. J Burn Care Res. 2020. PMID: 32615590
For some patients and contexts such as extended care on the battlefield, it would be preferable to remove devitalized tissue with a nonsurgical debridement agent. In this paper, a proprietary debridement gel (SN514) was evaluated for the ability to debride bo …
For some patients and contexts such as extended care on the battlefield, it would be preferable to remove devitalized tissue with a nonsurgi …
Application of hydrosurgery for burn wound debridement: An 8-year cohort analysis.
Legemate CM, Goei H, Gostelie OFE, Nijhuis THJ, van Baar ME, van der Vlies CH; Dutch Burn Repository Group. Legemate CM, et al. Burns. 2019 Feb;45(1):88-96. doi: 10.1016/j.burns.2018.08.015. Epub 2018 Oct 12. Burns. 2019. PMID: 30322740
All patients with burns that underwent surgical debridement were included. Data were collected using the national Dutch Burn Repository R3. ...CONCLUSION: The use of hydrosurgery for burn wound debridement prior to skin grafting is substantial. …
All patients with burns that underwent surgical debridement were included. Data were collected using the national Dutch Bur …
Amino acid buffered hypochlorite facilitates debridement of porcine infected burn wounds.
Alexander P L, Jonathan R, Gunnar K, Johan P E J. Alexander P L, et al. Burns. 2023 Sep;49(6):1363-1371. doi: 10.1016/j.burns.2022.11.011. Epub 2022 Dec 6. Burns. 2023. PMID: 36543728 Free article.
In this study we aim to evaluate the use of amino acid buffered hypochlorite (AABH) as a chemical enhancement for wound debridement in a porcine infected burn wound model. METHOD: A total of 60 full-thickness burn wounds, 3 cm in diameter, were created on fou …
In this study we aim to evaluate the use of amino acid buffered hypochlorite (AABH) as a chemical enhancement for wound debridement i …
3,275 results