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A flavivirus protein M-derived peptide directly permeabilizes mitochondrial membranes, triggers cell death and reduces human tumor growth in nude mice.
Brabant M, Baux L, Casimir R, Briand JP, Chaloin O, Porceddu M, Buron N, Chauvier D, Lassalle M, Lecoeur H, Langonné A, Dupont S, Déas O, Brenner C, Rebouillat D, Muller S, Borgne-Sanchez A, Jacotot E. Brabant M, et al. Among authors: buron n. Apoptosis. 2009 Oct;14(10):1190-203. doi: 10.1007/s10495-009-0394-y. Apoptosis. 2009. PMID: 19693674
HIV-1 Tat protein directly induces mitochondrial membrane permeabilization and inactivates cytochrome c oxidase.
Lecoeur H, Borgne-Sanchez A, Chaloin O, El-Khoury R, Brabant M, Langonné A, Porceddu M, Brière JJ, Buron N, Rebouillat D, Péchoux C, Deniaud A, Brenner C, Briand JP, Muller S, Rustin P, Jacotot E. Lecoeur H, et al. Among authors: buron n. Cell Death Dis. 2012 Mar 15;3(3):e282. doi: 10.1038/cddis.2012.21. Cell Death Dis. 2012. PMID: 22419111 Free PMC article.
The fourth isoform of the adenine nucleotide translocator inhibits mitochondrial apoptosis in cancer cells.
Gallerne C, Touat Z, Chen ZX, Martel C, Mayola E, Sharaf el dein O, Buron N, Le Bras M, Jacotot E, Borgne-Sanchez A, Lemoine A, Lemaire C, Pervaiz S, Brenner C. Gallerne C, et al. Among authors: buron n. Int J Biochem Cell Biol. 2010 May;42(5):623-9. doi: 10.1016/j.biocel.2009.12.024. Epub 2010 Jan 10. Int J Biochem Cell Biol. 2010. PMID: 20060930
Drug-induced hepatic steatosis in absence of severe mitochondrial dysfunction in HepaRG cells: proof of multiple mechanism-based toxicity.
Allard J, Bucher S, Massart J, Ferron PJ, Le Guillou D, Loyant R, Daniel Y, Launay Y, Buron N, Begriche K, Borgne-Sanchez A, Fromenty B. Allard J, et al. Among authors: buron n. Cell Biol Toxicol. 2021 Apr;37(2):151-175. doi: 10.1007/s10565-020-09537-1. Epub 2020 Jun 14. Cell Biol Toxicol. 2021. PMID: 32535746 Free PMC article.
19 results