Burrows FJ - Search Results

1

Marizomib activity as a single agent in malignant gliomas: ability to cross the blood-brain barrier.

Di K, Lloyd GK, Abraham V, MacLaren A, Burrows FJ, Desjardins A, Trikha M, Bota DA. Di K, et al. Among authors: burrows fj. Neuro Oncol. 2016 Jun;18(6):840-8. doi: 10.1093/neuonc/nov299. Epub 2015 Dec 17. Neuro Oncol. 2016. PMID: 26681765 Free PMC article.

2

Marizomib irreversibly inhibits proteasome to overcome compensatory hyperactivation in multiple myeloma and solid tumour patients.

Levin N, Spencer A, Harrison SJ, Chauhan D, Burrows FJ, Anderson KC, Reich SD, Richardson PG, Trikha M. Levin N, et al. Among authors: burrows fj. Br J Haematol. 2016 Sep;174(5):711-20. doi: 10.1111/bjh.14113. Epub 2016 May 9. Br J Haematol. 2016. PMID: 27161872 Free PMC article. Clinical Trial.

3

Dimeric ansamycins--a new class of antitumor Hsp90 modulators with prolonged inhibitory activity.

Zhang H, Yang YC, Zhang L, Fan J, Chung D, Choi D, Grecko R, Timony G, Karjian P, Boehm M, Burrows F. Zhang H, et al. Int J Cancer. 2007 Feb 15;120(4):918-26. doi: 10.1002/ijc.22392. Int J Cancer. 2007. PMID: 17131314 Free article.

4

Potent activity of a novel dimeric heat shock protein 90 inhibitor against head and neck squamous cell carcinoma in vitro and in vivo.

Yin X, Zhang H, Burrows F, Zhang L, Shores CG. Yin X, et al. Clin Cancer Res. 2005 May 15;11(10):3889-96. doi: 10.1158/1078-0432.CCR-04-2272. Clin Cancer Res. 2005. PMID: 15897590

5

Purified herpes simplex virus thymidine kinase retroviral particles: III. Characterization of bystander killing mechanisms in transfected tumor cells.

Burrows FJ, Gore M, Smiley WR, Kanemitsu MY, Jolly DJ, Read SB, Nicholas T, Kruse CA. Burrows FJ, et al. Cancer Gene Ther. 2002 Jan;9(1):87-95. doi: 10.1038/sj.cgt.7700401. Cancer Gene Ther. 2002. PMID: 11916247

6

BIIB021, an orally available, fully synthetic small-molecule inhibitor of the heat shock protein Hsp90.

Lundgren K, Zhang H, Brekken J, Huser N, Powell RE, Timple N, Busch DJ, Neely L, Sensintaffar JL, Yang YC, McKenzie A, Friedman J, Scannevin R, Kamal A, Hong K, Kasibhatla SR, Boehm MF, Burrows FJ. Lundgren K, et al. Among authors: burrows fj. Mol Cancer Ther. 2009 Apr;8(4):921-9. doi: 10.1158/1535-7163.MCT-08-0758. Mol Cancer Ther. 2009. PMID: 19372565

7

An investigation into the potential use of serum Hsp70 as a novel tumour biomarker for Hsp90 inhibitors.

Dakappagari N, Neely L, Tangri S, Lundgren K, Hipolito L, Estrellado A, Burrows F, Zhang H. Dakappagari N, et al. Biomarkers. 2010 Feb;15(1):31-8. doi: 10.3109/13547500903261347. Biomarkers. 2010. PMID: 19747088

8

7'-substituted benzothiazolothio- and pyridinothiazolothio-purines as potent heat shock protein 90 inhibitors.

Zhang L, Fan J, Vu K, Hong K, Le Brazidec JY, Shi J, Biamonte M, Busch DJ, Lough RE, Grecko R, Ran Y, Sensintaffar JL, Kamal A, Lundgren K, Burrows FJ, Mansfield R, Timony GA, Ulm EH, Kasibhatla SR, Boehm MF. Zhang L, et al. Among authors: burrows fj. J Med Chem. 2006 Aug 24;49(17):5352-62. doi: 10.1021/jm051146h. J Med Chem. 2006. PMID: 16913725

9

EC144 is a potent inhibitor of the heat shock protein 90.

Shi J, Van de Water R, Hong K, Lamer RB, Weichert KW, Sandoval CM, Kasibhatla SR, Boehm MF, Chao J, Lundgren K, Timple N, Lough R, Ibanez G, Boykin C, Burrows FJ, Kehry MR, Yun TJ, Harning EK, Ambrose C, Thompson J, Bixler SA, Dunah A, Snodgrass-Belt P, Arndt J, Enyedy IJ, Li P, Hong VS, McKenzie A, Biamonte MA. Shi J, et al. Among authors: burrows fj. J Med Chem. 2012 Sep 13;55(17):7786-95. doi: 10.1021/jm300810x. Epub 2012 Aug 31. J Med Chem. 2012. PMID: 22938030

10

BIIB021, a novel Hsp90 inhibitor, sensitizes head and neck squamous cell carcinoma to radiotherapy.

Yin X, Zhang H, Lundgren K, Wilson L, Burrows F, Shores CG. Yin X, et al. Int J Cancer. 2010 Mar 1;126(5):1216-25. doi: 10.1002/ijc.24815. Int J Cancer. 2010. PMID: 19662650 Free article.

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