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The clinical efficacy of first-generation carcinoembryonic antigen (CEACAM5)-specific CAR T cells is limited by poor persistence and transient pre-conditioning-dependent respiratory toxicity.
Thistlethwaite FC, Gilham DE, Guest RD, Rothwell DG, Pillai M, Burt DJ, Byatte AJ, Kirillova N, Valle JW, Sharma SK, Chester KA, Westwood NB, Halford SER, Nabarro S, Wan S, Austin E, Hawkins RE. Thistlethwaite FC, et al. Among authors: burt dj. Cancer Immunol Immunother. 2017 Nov;66(11):1425-1436. doi: 10.1007/s00262-017-2034-7. Epub 2017 Jun 28. Cancer Immunol Immunother. 2017. PMID: 28660319 Free PMC article. Clinical Trial.
Adoptive transfer of T(reg) depleted autologous T cells in advanced renal cell carcinoma.
Thistlethwaite FC, Elkord E, Griffiths RW, Burt DJ, Shablak AM, Campbell JD, Gilham DE, Austin EB, Stern PL, Hawkins RE. Thistlethwaite FC, et al. Among authors: burt dj. Cancer Immunol Immunother. 2008 May;57(5):623-34. doi: 10.1007/s00262-007-0400-6. Epub 2007 Sep 27. Cancer Immunol Immunother. 2008. PMID: 17899077 Clinical Trial.
CD8 T-cell recognition of human 5T4 oncofetal antigen.
Smyth LJ, Elkord E, Taher TE, Jiang HR, Burt DJ, Clayton A, van Veelen PA, de Ru A, Ossendorp F, Melief CJ, Drijfhout JW, Dermime S, Hawkins RE, Stern PL. Smyth LJ, et al. Among authors: burt dj. Int J Cancer. 2006 Oct 1;119(7):1638-47. doi: 10.1002/ijc.22018. Int J Cancer. 2006. PMID: 16646078 Free article.
32 results