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Broadly cross-reactive HIV-1-neutralizing human monoclonal Fab selected for binding to gp120-CD4-CCR5 complexes.
Moulard M, Phogat SK, Shu Y, Labrijn AF, Xiao X, Binley JM, Zhang MY, Sidorov IA, Broder CC, Robinson J, Parren PW, Burton DR, Dimitrov DS. Moulard M, et al. Among authors: burton dr. Proc Natl Acad Sci U S A. 2002 May 14;99(10):6913-8. doi: 10.1073/pnas.102562599. Epub 2002 May 7. Proc Natl Acad Sci U S A. 2002. PMID: 11997472 Free PMC article.
Antibodies, viruses and vaccines.
Burton DR. Burton DR. Nat Rev Immunol. 2002 Sep;2(9):706-13. doi: 10.1038/nri891. Nat Rev Immunol. 2002. PMID: 12209139 Review.
HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites.
Kwong PD, Doyle ML, Casper DJ, Cicala C, Leavitt SA, Majeed S, Steenbeke TD, Venturi M, Chaiken I, Fung M, Katinger H, Parren PW, Robinson J, Van Ryk D, Wang L, Burton DR, Freire E, Wyatt R, Sodroski J, Hendrickson WA, Arthos J. Kwong PD, et al. Among authors: burton dr. Nature. 2002 Dec 12;420(6916):678-82. doi: 10.1038/nature01188. Nature. 2002. PMID: 12478295
Conformation of PrP(C) on the cell surface as probed by antibodies.
Leclerc E, Peretz D, Ball H, Solforosi L, Legname G, Safar J, Serban A, Prusiner SB, Burton DR, Williamson RA. Leclerc E, et al. Among authors: burton dr. J Mol Biol. 2003 Feb 14;326(2):475-83. doi: 10.1016/s0022-2836(02)01365-7. J Mol Biol. 2003. PMID: 12559915
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