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Morphoproteomics and biomedical analytics confirm the mTORC2/Akt pathway as a resistance signature and activated ERK and STAT3 as concomitant prosurvival/antiapoptotic pathways in metastatic renal cell carcinoma (RCC) progressing on rapalogs: pathogenesis and therapeutic options.
Brown RE, Buryanek J, Tammisetti VS, McGuire MF, Csencsits-Smith K. Brown RE, et al. Among authors: buryanek j. Oncotarget. 2016 Jul 5;7(27):41612-41621. doi: 10.18632/oncotarget.9508. Oncotarget. 2016. PMID: 27223432 Free PMC article.
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