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Corticosteroids in respiratory diseases in children.
de Benedictis FM, Bush A. de Benedictis FM, et al. Among authors: bush a. Am J Respir Crit Care Med. 2012 Jan 1;185(1):12-23. doi: 10.1164/rccm.201107-1174CI. Am J Respir Crit Care Med. 2012. PMID: 21920920 Review.
There is a time lag before clinical response, and the washout of effects is also prolonged. Prompt relief in some conditions, such as croup, may be related to airway mucosal vasoconstriction through a nongenomic mechanism. ...
There is a time lag before clinical response, and the washout of effects is also prolonged. Prompt relief in some conditions, such as …
Increased interleukin-4 and decreased interferon-gamma in exhaled breath condensate of children with asthma.
Shahid SK, Kharitonov SA, Wilson NM, Bush A, Barnes PJ. Shahid SK, et al. Among authors: bush a. Am J Respir Crit Care Med. 2002 May 1;165(9):1290-3. doi: 10.1164/rccm.2108082. Am J Respir Crit Care Med. 2002. PMID: 11991881
Exhaled breath condensate analysis for noninvasive quantification of airway inflammation in asthma is a potentially useful research tool in children. ...Exhaled breath condensate analysis may have a useful role in studying allergic inflammation in childhood asthma.. …
Exhaled breath condensate analysis for noninvasive quantification of airway inflammation in asthma is a potentially useful research t …
Effects of recombinant human DNase and hypertonic saline on airway inflammation in children with cystic fibrosis.
Suri R, Marshall LJ, Wallis C, Metcalfe C, Bush A, Shute JK. Suri R, et al. Among authors: bush a. Am J Respir Crit Care Med. 2002 Aug 1;166(3):352-5. doi: 10.1164/rccm.2110015. Am J Respir Crit Care Med. 2002. PMID: 12153969 Clinical Trial.
In a randomized, crossover trial, 48 children with CF were allocated consecutively to 12 weeks of once-daily 2.5 mg rhDNase, alternate-day 2.5 mg rhDNase, and twice-daily 7% HS. ...
In a randomized, crossover trial, 48 children with CF were allocated consecutively to 12 weeks of once-daily 2.5 mg rhDNase, alternat …
Increased leukotrienes in exhaled breath condensate in childhood asthma.
Csoma Z, Kharitonov SA, Balint B, Bush A, Wilson NM, Barnes PJ. Csoma Z, et al. Among authors: bush a. Am J Respir Crit Care Med. 2002 Nov 15;166(10):1345-9. doi: 10.1164/rccm.200203-233OC. Epub 2002 Sep 5. Am J Respir Crit Care Med. 2002. PMID: 12406853
Cysteinyl leukotrienes (cys-LTs; LTC4, LTD4, and LTE4) are generated predominantly by mast cells and eosinophils and induce airway smooth muscle contraction, microvascular leakage, and mucous hypersecretion whereas leukotriene B4 (LTB4) is a potent chemoattractant of neutr …
Cysteinyl leukotrienes (cys-LTs; LTC4, LTD4, and LTE4) are generated predominantly by mast cells and eosinophils and induce airway smooth mu …
Relative ability of full and partial forced expiratory maneuvers to identify diminished airway function in infants with cystic fibrosis.
Ranganathan SC, Bush A, Dezateux C, Carr SB, Hoo AF, Lum S, Madge S, Price J, Stroobant J, Wade A, Wallis C, Wyatt H, Stocks J. Ranganathan SC, et al. Among authors: bush a. Am J Respir Crit Care Med. 2002 Nov 15;166(10):1350-7. doi: 10.1164/rccm.2202041. Am J Respir Crit Care Med. 2002. PMID: 12421744
A cross-sectional, prospective study design was used in which maximal flow at functional residual capacity (VmaxFRC) from the tidal technique and FVC, FEV0.5, FEF75, and FEF25-75 from the raised volume technique were measured in 47 infants with CF and 187 healthy infants o
A cross-sectional, prospective study design was used in which maximal flow at functional residual capacity (VmaxFRC) from the tidal t
Early thickening of the reticular basement membrane in children with difficult asthma.
Payne DN, Rogers AV, Adelroth E, Bandi V, Guntupalli KK, Bush A, Jeffery PK. Payne DN, et al. Among authors: bush a. Am J Respir Crit Care Med. 2003 Jan 1;167(1):78-82. doi: 10.1164/rccm.200205-414OC. Am J Respir Crit Care Med. 2003. PMID: 12502479
To investigate whether RBM thickening is present in children with difficult asthma and comparable to that seen in adults with asthma, we used light microscopy to measure RBM thickness in plastic-embedded endobronchial biopsy sections from 19 children with difficult asthma who wer …
To investigate whether RBM thickening is present in children with difficult asthma and comparable to that seen in adults with asthma, we use …
Dilution of respiratory solutes in exhaled condensates.
Zacharasiewicz A, Wilson N, Bush A. Zacharasiewicz A, et al. Among authors: bush a. Am J Respir Crit Care Med. 2003 Mar 1;167(5):802; author reply 802. doi: 10.1164/ajrccm.167.5.957. Am J Respir Crit Care Med. 2003. PMID: 12598224 No abstract available.
Free secretory component from cystic fibrosis sputa displays the cystic fibrosis glycosylation phenotype.
Marshall LJ, Perks B, Bodey K, Suri R, Bush A, Shute JK. Marshall LJ, et al. Among authors: bush a. Am J Respir Crit Care Med. 2004 Feb 1;169(3):399-406. doi: 10.1164/rccm.200305-619OC. Epub 2003 Nov 3. Am J Respir Crit Care Med. 2004. PMID: 14597481
The evolution of airway function in early childhood following clinical diagnosis of cystic fibrosis.
Ranganathan SC, Stocks J, Dezateux C, Bush A, Wade A, Carr S, Castle R, Dinwiddie R, Hoo AF, Lum S, Price J, Stroobant J, Wallis C. Ranganathan SC, et al. Among authors: bush a. Am J Respir Crit Care Med. 2004 Apr 15;169(8):928-33. doi: 10.1164/rccm.200309-1344OC. Epub 2004 Jan 30. Am J Respir Crit Care Med. 2004. PMID: 14754763
On longitudinal analysis, subjects with CF experienced a mean (95% confidence interval) reduction in FEV(0.5) of 20% (11, 28). ...
On longitudinal analysis, subjects with CF experienced a mean (95% confidence interval) reduction in FEV(0.5) of 20% (11, 28). ...
Quality control for spirometry in preschool children with and without lung disease.
Aurora P, Stocks J, Oliver C, Saunders C, Castle R, Chaziparasidis G, Bush A; London Cystic Fibrosis Collaboration. Aurora P, et al. Among authors: bush a. Am J Respir Crit Care Med. 2004 May 15;169(10):1152-9. doi: 10.1164/rccm.200310-1453OC. Epub 2004 Mar 17. Am J Respir Crit Care Med. 2004. PMID: 15028561
Start of test criteria for adults were inappropriate for this age group, with only 16 of 59 children producing a volume of back extrapolation as a proportion of forced vital capacity of less than 5%, whereas all but 4 could produce a volume of back extrapolat …
Start of test criteria for adults were inappropriate for this age group, with only 16 of 59 children producing a volume of back extra …
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