Carbapenem-resistant strain of Klebsiella oxytoca harboring carbapenem-hydrolyzing beta-lactamase KPC-2.
Yigit H, Queenan AM, Rasheed JK, Biddle JW, Domenech-Sanchez A, Alberti S, Bush K, Tenover FC.
Yigit H, et al. Among authors: bush k.
Antimicrob Agents Chemother. 2003 Dec;47(12):3881-9. doi: 10.1128/AAC.47.12.3881-3889.2003.
Antimicrob Agents Chemother. 2003.
PMID: 14638498
Free PMC article.
The amino acid sequence of KPC-2 showed a single amino acid difference, S174G, when compared with KPC-1, another carbapenem-hydrolyzing beta-lactamase from K. pneumoniae 1534. Hydrolysis studies showed that purified KPC-2 hydrolyzed not only carbapenems but also penicillin …
The amino acid sequence of KPC-2 showed a single amino acid difference, S174G, when compared with KPC-1, another carbapenem-hydrolyzing beta …