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Two-pore-domain K+ channels are a novel target for the anesthetic gases xenon, nitrous oxide, and cyclopropane.
Gruss M, Bushell TJ, Bright DP, Lieb WR, Mathie A, Franks NP. Gruss M, et al. Among authors: bushell tj. Mol Pharmacol. 2004 Feb;65(2):443-52. doi: 10.1124/mol.65.2.443. Mol Pharmacol. 2004. PMID: 14742687
Pharmacological characterization of a non-inactivating outward current observed in mouse cerebellar Purkinje neurones.
Bushell T, Clarke C, Mathie A, Robertson B. Bushell T, et al. Br J Pharmacol. 2002 Feb;135(3):705-12. doi: 10.1038/sj.bjp.0704518. Br J Pharmacol. 2002. PMID: 11834618 Free PMC article.
Determinants of the anesthetic sensitivity of neuronal nicotinic acetylcholine receptors.
Downie DL, Vicente-Agullo F, Campos-Caro A, Bushell TJ, Lieb WR, Franks NP. Downie DL, et al. Among authors: bushell tj. J Biol Chem. 2002 Mar 22;277(12):10367-73. doi: 10.1074/jbc.M107847200. Epub 2001 Dec 10. J Biol Chem. 2002. PMID: 11741933
Two-pore potassium ion channels are inhibited by both G(q/11)- and G(i)-coupled P2Y receptors.
Shrestha SS, Parmar M, Kennedy C, Bushell TJ. Shrestha SS, et al. Among authors: bushell tj. Mol Cell Neurosci. 2010 Apr;43(4):363-9. doi: 10.1016/j.mcn.2010.01.003. Epub 2010 Jan 22. Mol Cell Neurosci. 2010. PMID: 20097289
Indirect modulation of neuronal excitability and synaptic transmission in the hippocampus by activation of proteinase-activated receptor-2.
Gan J, Greenwood SM, Cobb SR, Bushell TJ. Gan J, et al. Among authors: bushell tj. Br J Pharmacol. 2011 Jul;163(5):984-94. doi: 10.1111/j.1476-5381.2011.01293.x. Br J Pharmacol. 2011. PMID: 21366553 Free PMC article.
Cannabidiol inhibits synaptic transmission in rat hippocampal cultures and slices via multiple receptor pathways.
Ledgerwood CJ, Greenwood SM, Brett RR, Pratt JA, Bushell TJ. Ledgerwood CJ, et al. Among authors: bushell tj. Br J Pharmacol. 2011 Jan;162(1):286-94. doi: 10.1111/j.1476-5381.2010.01015.x. Br J Pharmacol. 2011. PMID: 20825410 Free PMC article.
Lymphocytes protect cortical neurons against excitotoxicity mediated by kainic acid, an in vitro model for neurodegeneration.
Shrestha R, Millington O, Brewer J, Bushell T. Shrestha R, et al. Kathmandu Univ Med J (KUMJ). 2013 Apr-Jun;11(42):132-8. doi: 10.3126/kumj.v11i2.12488. Kathmandu Univ Med J (KUMJ). 2013. PMID: 24096220
Advances in imaging of new targets for pharmacological intervention in stroke: real-time tracking of T-cells in the ischaemic brain.
Ortolano F, Maffia P, Dever G, Rodolico G, Millington OR, De Simoni MG, Brewer JM, Bushell TJ, Garside P, Carswell HV. Ortolano F, et al. Among authors: bushell tj. Br J Pharmacol. 2010 Feb;159(4):808-11. doi: 10.1111/j.1476-5381.2009.00527.x. Epub 2009 Dec 10. Br J Pharmacol. 2010. PMID: 20015295 Free PMC article.
Toll-like receptor 3 activation impairs excitability and synaptic activity via TRIF signalling in immature rat and human neurons.
Ritchie L, Tate R, Chamberlain LH, Robertson G, Zagnoni M, Sposito T, Wray S, Wright JA, Bryant CE, Gay NJ, Bushell TJ. Ritchie L, et al. Among authors: bushell tj. Neuropharmacology. 2018 Jun;135:1-10. doi: 10.1016/j.neuropharm.2018.02.025. Epub 2018 Mar 2. Neuropharmacology. 2018. PMID: 29505789
Proteinase-activated receptor 2 is involved in the behavioural changes associated with sickness behaviour.
Abulkassim R, Brett R, MacKenzie SM, Bushell TJ. Abulkassim R, et al. Among authors: bushell tj. J Neuroimmunol. 2016 Jun 15;295-296:139-47. doi: 10.1016/j.jneuroim.2016.04.016. Epub 2016 Apr 27. J Neuroimmunol. 2016. PMID: 27235359 Free article.
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