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Combined mitoxantrone and anti-TGFβ treatment with PD-1 blockade enhances antitumor immunity by remodelling the tumor immune landscape in neuroblastoma.
Lucarini V, Melaiu O, D'Amico S, Pastorino F, Tempora P, Scarsella M, Pezzullo M, De Ninno A, D'Oria V, Cilli M, Emionite L, Infante P, Di Marcotullio L, De Ioris MA, Barillari G, Alaggio R, Businaro L, Ponzoni M, Locatelli F, Fruci D. Lucarini V, et al. Among authors: businaro l. J Exp Clin Cancer Res. 2022 Nov 17;41(1):326. doi: 10.1186/s13046-022-02525-9. J Exp Clin Cancer Res. 2022. PMID: 36397148 Free PMC article.
Type I IFNs promote cancer cell stemness by triggering the epigenetic regulator KDM1B.
Musella M, Guarracino A, Manduca N, Galassi C, Ruggiero E, Potenza A, Maccafeo E, Manic G, Mattiello L, Soliman Abdel Rehim S, Signore M, Pietrosanto M, Helmer-Citterich M, Pallocca M, Fanciulli M, Bruno T, De Nicola F, Corleone G, Di Benedetto A, Ercolani C, Pescarmona E, Pizzuti L, Guidi F, Sperati F, Vitale S, Macchia D, Spada M, Schiavoni G, Mattei F, De Ninno A, Businaro L, Lucarini V, Bracci L, Aricò E, Ziccheddu G, Facchiano F, Rossi S, Sanchez M, Boe A, Biffoni M, De Maria R, Vitale I, Sistigu A. Musella M, et al. Among authors: businaro l. Nat Immunol. 2022 Sep;23(9):1379-1392. doi: 10.1038/s41590-022-01290-3. Epub 2022 Aug 24. Nat Immunol. 2022. PMID: 36002648 Free PMC article.
Oncoimmunology Meets Organs-on-Chip.
Mattei F, Andreone S, Mencattini A, De Ninno A, Businaro L, Martinelli E, Schiavoni G. Mattei F, et al. Among authors: businaro l. Front Mol Biosci. 2021 Mar 26;8:627454. doi: 10.3389/fmolb.2021.627454. eCollection 2021. Front Mol Biosci. 2021. PMID: 33842539 Free PMC article. Review.
Accelerating the experimental responses on cell behaviors: a long-term prediction of cell trajectories using Social Generative Adversarial Network.
Comes MC, Filippi J, Mencattini A, Corsi F, Casti P, De Ninno A, Di Giuseppe D, D'Orazio M, Ghibelli L, Mattei F, Schiavoni G, Businaro L, Di Natale C, Martinelli E. Comes MC, et al. Among authors: businaro l. Sci Rep. 2020 Sep 24;10(1):15635. doi: 10.1038/s41598-020-72605-3. Sci Rep. 2020. PMID: 32973301 Free PMC article.
Organ-on-chip model shows that ATP release through connexin hemichannels drives spontaneous Ca2+ signaling in non-sensory cells of the greater epithelial ridge in the developing cochlea.
Mazzarda F, D'Elia A, Massari R, De Ninno A, Bertani FR, Businaro L, Ziraldo G, Zorzi V, Nardin C, Peres C, Chiani F, Tettey-Matey A, Raspa M, Scavizzi F, Soluri A, Salvatore AM, Yang J, Mammano F. Mazzarda F, et al. Among authors: businaro l. Lab Chip. 2020 Aug 11;20(16):3011-3023. doi: 10.1039/d0lc00427h. Lab Chip. 2020. PMID: 32700707
45 results