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Significant Reduction in Helicobacter pylori Load in Humans with Non-viable Lactobacillus reuteri DSM17648: A Pilot Study.
Holz C, Busjahn A, Mehling H, Arya S, Boettner M, Habibi H, Lang C. Holz C, et al. Probiotics Antimicrob Proteins. 2015 Jun;7(2):91-100. doi: 10.1007/s12602-014-9181-3. Probiotics Antimicrob Proteins. 2015. PMID: 25481036 Free PMC article. Clinical Trial.
Lactobacillus reuteri DSM17648 was identified as a highly specific binding antagonist to H. pylori among more than 700 wild-type strains of Lactobacillus species. Applying a stringent screening procedure, the strain DSM17648 was identified as selective binder to H. …
Lactobacillus reuteri DSM17648 was identified as a highly specific binding antagonist to H. pylori among more than 700 wild-type stra …
Non-viable Lactobacillus reuteri DSMZ 17648 (Pylopass™) as a new approach to Helicobacter pylori control in humans.
Mehling H, Busjahn A. Mehling H, et al. Nutrients. 2013 Aug 2;5(8):3062-73. doi: 10.3390/nu5083062. Nutrients. 2013. PMID: 23917169 Free PMC article. Clinical Trial.
Prevalence of infections by Helicobacter pylori, a pathogen involved in a number of gastrointestinal diseases, remains high in developing countries. ...These results confirm the potential of Pylopass™ as a novel way to reduce the load of H. pylori....
Prevalence of infections by Helicobacter pylori, a pathogen involved in a number of gastrointestinal diseases, remains high in …
Single lipoprotein apheresis session improves cardiac microvascular function in patients with elevated lipoprotein(a): detection by stress/rest perfusion magnetic resonance imaging.
Bohl S, Kassner U, Eckardt R, Utz W, Mueller-Nordhorn J, Busjahn A, Thomas HP, Abdel-Aty H, Klingel R, Marcovina S, Dietz R, Steinhagen-Thiessen E, Schulz-Menger J, Vogt A. Bohl S, et al. Ther Apher Dial. 2009 Apr;13(2):129-37. doi: 10.1111/j.1744-9987.2009.00667.x. Ther Apher Dial. 2009. PMID: 19379152 Clinical Trial.
The aim of this study was to explore the effects of a single lipoprotein apheresis session on myocardial stress/rest (S/R) perfusion in patients with elevated lipoprotein(a) (Lp(a)) and coronary artery disease using cardiac magnetic resonance imaging. Twenty …
The aim of this study was to explore the effects of a single lipoprotein apheresis session on myocardial stress/rest (S/R) perfusion …
A pilot study of chronic, low-dose epoetin-{beta} following percutaneous coronary intervention suggests safety, feasibility, and efficacy in patients with symptomatic ischaemic heart failure.
Bergmann MW, Haufe S, von Knobelsdorff-Brenkenhoff F, Mehling H, Wassmuth R, Münch I, Busjahn A, Schulz-Menger J, Jordan J, Luft FC, Dietz R. Bergmann MW, et al. Eur J Heart Fail. 2011 May;13(5):560-8. doi: 10.1093/eurjhf/hfr002. Eur J Heart Fail. 2011. PMID: 21505058 Clinical Trial.
METHODS AND RESULTS: We performed a randomized, placebo-controlled, double-blind, single-centre study of 35 IU/kg body weight epoetin-β given subcutaneously once weekly for 6 months started within 3 weeks after successful percutaneous coronary intervention (PCI). Patients …
METHODS AND RESULTS: We performed a randomized, placebo-controlled, double-blind, single-centre study of 35 IU/kg body weight epoetin …
Regulation of nutrition-associated receptors in blood monocytes of normal weight and obese humans.
Pivovarova O, Hornemann S, Weimer S, Lu Y, Murahovschi V, Zhuk S, Seltmann AC, Malashicheva A, Kostareva A, Kruse M, Busjahn A, Rudovich N, Pfeiffer AF. Pivovarova O, et al. Peptides. 2015 Mar;65:12-9. doi: 10.1016/j.peptides.2014.11.009. Epub 2015 Jan 22. Peptides. 2015. PMID: 25620618 Clinical Trial.
Correlations of the receptor expression in monocytes with a range of metabolic and inflammatory markers were found. In non-obese subjects, the dietary switch to LC/HFD induced the increase of GPR43 and VIPR1 expression in monocytes. ...
Correlations of the receptor expression in monocytes with a range of metabolic and inflammatory markers were found. In non-obese subj …
Genetic influences on the pharmacokinetics of orally and intravenously administered digoxin as exhibited by monozygotic twins.
Birkenfeld AL, Jordan J, Hofmann U, Busjahn A, Franke G, Krüger N, Igel S, Mürdter T, Drescher S, Shi S, Engeli S, Schwab M, Eichelbaum M, Luft FC, Fromm MF. Birkenfeld AL, et al. Clin Pharmacol Ther. 2009 Dec;86(6):605-8. doi: 10.1038/clpt.2009.170. Epub 2009 Sep 23. Clin Pharmacol Ther. 2009. PMID: 19776737 Clinical Trial.
We studied the disposition of digoxin, a frequently used probe drug for P-glycoprotein function in humans, in monozygotic (MZ) twins and found that digoxin pharmacokinetics after oral and intravenous administration are highly correlated within MZ twins, supporting the hypo …
We studied the disposition of digoxin, a frequently used probe drug for P-glycoprotein function in humans, in monozygotic (MZ) twins …
Left ventricular mass and function with reduced-fat or reduced-carbohydrate hypocaloric diets in overweight and obese subjects.
Haufe S, Utz W, Engeli S, Kast P, Böhnke J, Pofahl M, Traber J, Haas V, Hermsdorf M, Mähler A, Busjahn A, Wiesner S, Otto C, Mehling H, Luft FC, Boschmann M, Schulz-Menger J, Jordan J. Haufe S, et al. Hypertension. 2012 Jan;59(1):70-5. doi: 10.1161/HYPERTENSIONAHA.111.178616. Epub 2011 Nov 7. Hypertension. 2012. PMID: 22068866 Clinical Trial.
Ninety subjects completing the intervention period had a full cardiac MRI data set. Subjects lost 7.3±4.0 kg (7.9±3.8%) with reduced-carbohydrate diet and 6.2±4.2 kg (6.7±4.4%) with reduced-fat diet (P<0.001 within each group; P=not significant between interventions). . …
Ninety subjects completing the intervention period had a full cardiac MRI data set. Subjects lost 7.3±4.0 kg (7.9±3.8%) with reduced- …
Heart failure awareness survey in Germany: general knowledge on heart failure remains poor.
Zelenak C, Radenovic S, Musial-Bright L, Tahirovic E, Sacirovic M, Lee CB, Jahandar-Lashki D, Inkrot S, Trippel TD, Busjahn A, Hashemi D, Wachter R, Pankuweit S, Störk S, Pieske B, Edelmann F, Düngen HD. Zelenak C, et al. ESC Heart Fail. 2017 Aug;4(3):224-231. doi: 10.1002/ehf2.12144. Epub 2017 Mar 22. ESC Heart Fail. 2017. PMID: 28772053 Free PMC article.
METHODS AND RESULTS: In 2007, 2012, and 2015, respectively, 2531, 359, and 171 respondents answered questions about causes, presentation, prognosis, and treatment of HF from a survey developed by the German Competence Network HF. ...
METHODS AND RESULTS: In 2007, 2012, and 2015, respectively, 2531, 359, and 171 respondents answered questions about causes, presentation, pr …
Anti-ß1-Adrenoreceptor auto-Antibodies in elderly heart failure patients.
Trippel TD, Mueller DN, Obradovic D, Edelmann F, Tahirovic E, Wilck N, Riemekasten G, Dragun D, Busjahn A, Heidecke H, Junker J, Pieske B, Dungen HD, Dechend R. Trippel TD, et al. Among authors: busjahn a. Front Biosci (Landmark Ed). 2019 Mar 1;24:1037-1049. Front Biosci (Landmark Ed). 2019. PMID: 30844728 Clinical Trial.
Left ventricular outflow tract planimetry by cardiovascular magnetic resonance differentiates obstructive from non-obstructive hypertrophic cardiomyopathy.
Schulz-Menger J, Abdel-Aty H, Busjahn A, Wassmuth R, Pilz B, Dietz R, Friedrich MG. Schulz-Menger J, et al. J Cardiovasc Magn Reson. 2006;8(5):741-6. doi: 10.1080/10976640600737383. J Cardiovasc Magn Reson. 2006. PMID: 16891234
A cutoff value of 2.7 cm2 identified obstruction as defined by echocardiography with 100% accuracy. CMR planimetry at rest is a promising tool to evaluate patients with hypertrophic cardiomyopathy....
A cutoff value of 2.7 cm2 identified obstruction as defined by echocardiography with 100% accuracy. CMR planimetry at rest is a
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