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Regulation of cell number in Drosophila.
Busturia A, Lawrence PA. Busturia A, et al. Nature. 1994 Aug 18;370(6490):561-3. doi: 10.1038/370561a0. Nature. 1994. PMID: 7914352
In most insects, growth of the epidermis is so controlled that, at each moult, there is a precise and proportionate increase in cell number. ...Here we used embryos with a reduced number of cells in the abdominal primordia to determine whether they can regulate towa …
In most insects, growth of the epidermis is so controlled that, at each moult, there is a precise and proportionate increase in cell …
MicroRNA miR-7 contributes to the control of Drosophila wing growth.
Aparicio R, Simoes Da Silva CJ, Busturia A. Aparicio R, et al. Among authors: busturia a. Dev Dyn. 2015 Jan;244(1):21-30. doi: 10.1002/dvdy.24214. Epub 2014 Nov 4. Dev Dyn. 2015. PMID: 25302682 Free article.
Functional characterization of the dRYBP gene in Drosophila.
González I, Aparicio R, Busturia A. González I, et al. Among authors: busturia a. Genetics. 2008 Jul;179(3):1373-88. doi: 10.1534/genetics.107.082966. Epub 2008 Jun 18. Genetics. 2008. PMID: 18562658 Free PMC article.
The Drosophila dRYBP gene has been described to function as a Polycomb-dependent transcriptional repressor. To determine the in vivo function of the dRYBP gene, we have generated mutations and analyzed the associated phenotypes. Homozygous null mutants die progressively th …
The Drosophila dRYBP gene has been described to function as a Polycomb-dependent transcriptional repressor. To determine the in vivo …
Function of the Trithorax-like gene during Drosophila development.
Bejarano F, Busturia A. Bejarano F, et al. Among authors: busturia a. Dev Biol. 2004 Apr 15;268(2):327-41. doi: 10.1016/j.ydbio.2004.01.006. Dev Biol. 2004. PMID: 15063171
To explain Trithorax-like gene function, we propose a model where very early in development, GAGA factor probably establishes a chromatin ground state for transcription. ...We also suggest that GAGA factor may not have a dual activator/repressor function. Rat …
To explain Trithorax-like gene function, we propose a model where very early in development, GAGA factor probably establishes a
Genetic and molecular characterization of a novel iab-8 regulatory domain in the Abdominal-B gene of Drosophila melanogaster.
Estrada B, Casares F, Busturia A, Sánchez-Herrero E. Estrada B, et al. Among authors: busturia a. Development. 2002 Nov;129(22):5195-204. Development. 2002. PMID: 12399311
We have analyzed the expression and mutant phenotype of a P-lacZ element inserted close to the Abdominal-B m origin of transcription and of derivatives of this transposon. Some of these derivatives represent a particular class of mutations in the bithorax complex, b …
We have analyzed the expression and mutant phenotype of a P-lacZ element inserted close to the Abdominal-B m origin of transcription …
Silencers in abdominal-B, a homeotic Drosophila gene.
Busturia A, Bienz M. Busturia A, et al. EMBO J. 1993 Apr;12(4):1415-25. EMBO J. 1993. PMID: 8096812 Free PMC article.
One of the Abd-B fragments, called IAB5, mediates a beta-gal pattern restricted along the body axis to the Abd-B expression domain. ...IAB5 and two other fragments called MCP and FAB show region-specific silencing activity: they suppress at a distance beta-gal expre …
One of the Abd-B fragments, called IAB5, mediates a beta-gal pattern restricted along the body axis to the Abd-B expression domain. . …
Double and triple mutant combinations of bithorax complex of Drosophila.
Casanova J, Sánchez-Herrero E, Busturia A, Morata G. Casanova J, et al. Among authors: busturia a. EMBO J. 1987 Oct;6(10):3103-9. EMBO J. 1987. PMID: 14650432 Free PMC article.
Embryos hemizygous for the triple combination exhibit a metameric pattern consisting of parasegments 5-12 being transformed into parasegment 4. ...The abd-A Abd-B combination exhibits the same phenotype of DpP10 DfP9, lacking all the abdominal functions except those …
Embryos hemizygous for the triple combination exhibit a metameric pattern consisting of parasegments 5-12 being transformed into para …
Ectopic expression of homeotic genes caused by the elimination of the Polycomb gene in Drosophila imaginal epidermis.
Busturia A, Morata G. Busturia A, et al. Development. 1988 Dec;104(4):713-20. Development. 1988. PMID: 2908325
Adding contributions of Ultrabithorax, abdominal-A and Abdominal-B results in thoracic or abdominal patterns. We have established a hierarchical order among these genes: Antp less than Scr less than Ubx less than abd-A less than Abd-B. ...
Adding contributions of Ultrabithorax, abdominal-A and Abdominal-B results in thoracic or abdominal patterns. We have established …
Structure and function of the bithorax complex genes of Drosophila.
Busturia A, Casanova J, Sánchez-Herrero E, Morata G. Busturia A, et al. Ciba Found Symp. 1989;144:227-38; discussion 239-42, 290-5. doi: 10.1002/9780470513798.ch13. Ciba Found Symp. 1989. PMID: 2673679 Review.
A third regulatory element, called Cbx-like, prevents the expression of Ubx anterior to parasegment 5. The gene abd-A is not as well known, but genetic and molecular studies indicate at least one cis-regulatory region downstream of the 3' end of the transcription un
A third regulatory element, called Cbx-like, prevents the expression of Ubx anterior to parasegment 5. The gene abd-A is not a
Genetic structure of the abd-A gene of Drosophila.
Busturia A, Casanova J, Sánchez-Herrero E, González R, Morata G. Busturia A, et al. Development. 1989 Nov;107(3):575-83. Development. 1989. PMID: 2575516
We report the embryonic and adult phenotypes of a number of mutations of the abd-A gene of the bithorax complex. Some of them result in loss of abd-A function in the whole abd-A domain and are usually lethal. These probably eliminate or inactivate abd- …
We report the embryonic and adult phenotypes of a number of mutations of the abd-A gene of the bithorax complex. Some of them …
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