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Functional polymorphism of the human arylamine N-acetyltransferase type 1 gene caused by C190T and G560A mutations.
Butcher NJ, Ilett KF, Minchin RF. Butcher NJ, et al. Pharmacogenetics. 1998 Feb;8(1):67-72. doi: 10.1097/00008571-199802000-00009. Pharmacogenetics. 1998. PMID: 9511183
Substrate-dependent regulation of human arylamine N-acetyltransferase-1 in cultured cells.
Butcher NJ, Ilett KF, Minchin RF. Butcher NJ, et al. Mol Pharmacol. 2000 Mar;57(3):468-73. doi: 10.1124/mol.57.3.468. Mol Pharmacol. 2000. PMID: 10692486
Inactivation of human arylamine N-acetyltransferase 1 by the hydroxylamine of p-aminobenzoic acid.
Butcher NJ, Ilett KF, Minchin RF. Butcher NJ, et al. Biochem Pharmacol. 2000 Dec 15;60(12):1829-36. doi: 10.1016/s0006-2952(00)00501-3. Biochem Pharmacol. 2000. PMID: 11108798
Pharmacogenetics of the arylamine N-acetyltransferases.
Butcher NJ, Boukouvala S, Sim E, Minchin RF. Butcher NJ, et al. Pharmacogenomics J. 2002;2(1):30-42. doi: 10.1038/sj.tpj.6500053. Pharmacogenomics J. 2002. PMID: 11990379 Review.
Identification of a minimal promoter sequence for the human N-acetyltransferase Type I gene that binds AP-1 (activator protein 1) and YY-1 (Yin and Yang 1).
Butcher NJ, Arulpragasam A, Pope C, Minchin RF. Butcher NJ, et al. Biochem J. 2003 Dec 1;376(Pt 2):441-8. doi: 10.1042/BJ20030650. Biochem J. 2003. PMID: 12946272 Free PMC article.
Proteasomal degradation of N-acetyltransferase 1 is prevented by acetylation of the active site cysteine: a mechanism for the slow acetylator phenotype and substrate-dependent down-regulation.
Butcher NJ, Arulpragasam A, Minchin RF. Butcher NJ, et al. J Biol Chem. 2004 May 21;279(21):22131-7. doi: 10.1074/jbc.M312858200. Epub 2004 Mar 23. J Biol Chem. 2004. PMID: 15039438
Genomic organization of human arylamine N-acetyltransferase Type I reveals alternative promoters that generate different 5'-UTR splice variants with altered translational activities.
Butcher NJ, Arulpragasam A, Goh HL, Davey T, Minchin RF. Butcher NJ, et al. Biochem J. 2005 Apr 1;387(Pt 1):119-27. doi: 10.1042/BJ20040903. Biochem J. 2005. PMID: 15487985 Free PMC article.
Induction of human arylamine N-acetyltransferase type I by androgens in human prostate cancer cells.
Butcher NJ, Tetlow NL, Cheung C, Broadhurst GM, Minchin RF. Butcher NJ, et al. Cancer Res. 2007 Jan 1;67(1):85-92. doi: 10.1158/0008-5472.CAN-06-2635. Cancer Res. 2007. PMID: 17210686
Arylamine N-acetyltransferase I.
Minchin RF, Hanna PE, Dupret JM, Wagner CR, Rodrigues-Lima F, Butcher NJ. Minchin RF, et al. Among authors: butcher nj. Int J Biochem Cell Biol. 2007;39(11):1999-2005. doi: 10.1016/j.biocel.2006.12.006. Epub 2007 Jan 20. Int J Biochem Cell Biol. 2007. PMID: 17392017
Regulation of arylamine N-acetyltransferases.
Butcher NJ, Tiang J, Minchin RF. Butcher NJ, et al. Curr Drug Metab. 2008 Jul;9(6):498-504. doi: 10.2174/138920008784892128. Curr Drug Metab. 2008. PMID: 18680469 Review.
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