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Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice.
Butovsky O, Jedrychowski MP, Cialic R, Krasemann S, Murugaiyan G, Fanek Z, Greco DJ, Wu PM, Doykan CE, Kiner O, Lawson RJ, Frosch MP, Pochet N, Fatimy RE, Krichevsky AM, Gygi SP, Lassmann H, Berry J, Cudkowicz ME, Weiner HL. Butovsky O, et al. Ann Neurol. 2015 Jan;77(1):75-99. doi: 10.1002/ana.24304. Epub 2014 Nov 27. Ann Neurol. 2015. PMID: 25381879 Free PMC article.
The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases.
Krasemann S, Madore C, Cialic R, Baufeld C, Calcagno N, El Fatimy R, Beckers L, O'Loughlin E, Xu Y, Fanek Z, Greco DJ, Smith ST, Tweet G, Humulock Z, Zrzavy T, Conde-Sanroman P, Gacias M, Weng Z, Chen H, Tjon E, Mazaheri F, Hartmann K, Madi A, Ulrich JD, Glatzel M, Worthmann A, Heeren J, Budnik B, Lemere C, Ikezu T, Heppner FL, Litvak V, Holtzman DM, Lassmann H, Weiner HL, Ochando J, Haass C, Butovsky O. Krasemann S, et al. Among authors: butovsky o, o loughlin e. Immunity. 2017 Sep 19;47(3):566-581.e9. doi: 10.1016/j.immuni.2017.08.008. Immunity. 2017. PMID: 28930663 Free PMC article.
Microglial Phenotypes and Functions in Multiple Sclerosis.
O'Loughlin E, Madore C, Lassmann H, Butovsky O. O'Loughlin E, et al. Among authors: butovsky o. Cold Spring Harb Perspect Med. 2018 Feb 1;8(2):a028993. doi: 10.1101/cshperspect.a028993. Cold Spring Harb Perspect Med. 2018. PMID: 29419406 Free PMC article. Review.
Pro-inflammatory activation of microglia in the brain of patients with sepsis.
Zrzavy T, Höftberger R, Berger T, Rauschka H, Butovsky O, Weiner H, Lassmann H. Zrzavy T, et al. Among authors: butovsky o. Neuropathol Appl Neurobiol. 2019 Apr;45(3):278-290. doi: 10.1111/nan.12502. Epub 2018 Jun 19. Neuropathol Appl Neurobiol. 2019. PMID: 29804289 Free PMC article.
Acute microglia ablation induces neurodegeneration in the somatosensory system.
Rubino SJ, Mayo L, Wimmer I, Siedler V, Brunner F, Hametner S, Madi A, Lanser A, Moreira T, Donnelly D, Cox L, Rezende RM, Butovsky O, Lassmann H, Weiner HL. Rubino SJ, et al. Among authors: butovsky o. Nat Commun. 2018 Nov 1;9(1):4578. doi: 10.1038/s41467-018-05929-4. Nat Commun. 2018. PMID: 30385785 Free PMC article.
87 results