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Cross-species functional analysis of cancer-associated fibroblasts identifies a critical role for CLCF1 and IL-6 in non-small cell lung cancer in vivo.
Vicent S, Sayles LC, Vaka D, Khatri P, Gevaert O, Chen R, Zheng Y, Gillespie AK, Clarke N, Xu Y, Shrager J, Hoang CD, Plevritis S, Butte AJ, Sweet-Cordero EA. Vicent S, et al. Among authors: butte aj. Cancer Res. 2012 Nov 15;72(22):5744-56. doi: 10.1158/0008-5472.CAN-12-1097. Epub 2012 Sep 7. Cancer Res. 2012. PMID: 22962265 Free PMC article.
A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors.
Jahchan NS, Dudley JT, Mazur PK, Flores N, Yang D, Palmerton A, Zmoos AF, Vaka D, Tran KQ, Zhou M, Krasinska K, Riess JW, Neal JW, Khatri P, Park KS, Butte AJ, Sage J. Jahchan NS, et al. Among authors: butte aj. Cancer Discov. 2013 Dec;3(12):1364-77. doi: 10.1158/2159-8290.CD-13-0183. Epub 2013 Sep 26. Cancer Discov. 2013. PMID: 24078773 Free PMC article.
Systematic pan-cancer analysis of tumour purity.
Aran D, Sirota M, Butte AJ. Aran D, et al. Among authors: butte aj. Nat Commun. 2015 Dec 4;6:8971. doi: 10.1038/ncomms9971. Nat Commun. 2015. PMID: 26634437 Free PMC article.
Widespread parainflammation in human cancer.
Aran D, Lasry A, Zinger A, Biton M, Pikarsky E, Hellman A, Butte AJ, Ben-Neriah Y. Aran D, et al. Among authors: butte aj. Genome Biol. 2016 Jul 8;17(1):145. doi: 10.1186/s13059-016-0995-z. Genome Biol. 2016. PMID: 27386949 Free PMC article.
Digitally deconvolving the tumor microenvironment.
Aran D, Butte AJ. Aran D, et al. Among authors: butte aj. Genome Biol. 2016 Aug 22;17(1):175. doi: 10.1186/s13059-016-1036-7. Genome Biol. 2016. PMID: 27549319 Free PMC article. Review.
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