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The free radical antioxidant vitamin E protects cortical synaptosomal membranes from amyloid beta-peptide(25-35) toxicity but not from hydroxynonenal toxicity: relevance to the free radical hypothesis of Alzheimer's disease.
Subramaniam R, Koppal T, Green M, Yatin S, Jordan B, Drake J, Butterfield DA. Subramaniam R, et al. Among authors: Butterfield DA. Neurochem Res. 1998 Nov;23(11):1403-10. doi: 10.1023/a:1020754807671. Neurochem Res. 1998. PMID: 9814551
Structural and functional changes in proteins induced by free radical-mediated oxidative stress and protective action of the antioxidants N-tert-butyl-alpha-phenylnitrone and vitamin E.
Butterfield DA, Koppal T, Howard B, Subramaniam R, Hall N, Hensley K, Yatin S, Allen K, Aksenov M, Aksenova M, Carney J. Butterfield DA, et al. Ann N Y Acad Sci. 1998 Nov 20;854:448-62. doi: 10.1111/j.1749-6632.1998.tb09924.x. Ann N Y Acad Sci. 1998. PMID: 9928452 Review.
Elevated oxidative stress in models of normal brain aging and Alzheimer's disease.
Butterfield DA, Howard B, Yatin S, Koppal T, Drake J, Hensley K, Aksenov M, Aksenova M, Subramaniam R, Varadarajan S, Harris-White ME, Pedigo NW Jr, Carney JM. Butterfield DA, et al. Life Sci. 1999;65(18-19):1883-92. doi: 10.1016/s0024-3205(99)00442-7. Life Sci. 1999. PMID: 10576432 Review.
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