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Prediction of the in vivo OATP1B1-mediated drug-drug interaction potential of an investigational drug against a range of statins.
Sharma P, Butters CJ, Smith V, Elsby R, Surry D. Sharma P, et al. Among authors: butters cj. Eur J Pharm Sci. 2012 Aug 30;47(1):244-55. doi: 10.1016/j.ejps.2012.04.003. Epub 2012 Apr 19. Eur J Pharm Sci. 2012. PMID: 22538052
Validation of membrane vesicle-based breast cancer resistance protein and multidrug resistance protein 2 assays to assess drug transport and the potential for drug-drug interaction to support regulatory submissions.
Elsby R, Smith V, Fox L, Stresser D, Butters C, Sharma P, Surry DD. Elsby R, et al. Xenobiotica. 2011 Sep;41(9):764-83. doi: 10.3109/00498254.2011.578761. Epub 2011 May 25. Xenobiotica. 2011. PMID: 21612343
The utility of in vitro data in making accurate predictions of human P-glycoprotein-mediated drug-drug interactions: a case study for AZD5672.
Elsby R, Gillen M, Butters C, Imisson G, Sharma P, Smith V, Surry DD. Elsby R, et al. Drug Metab Dispos. 2011 Feb;39(2):275-82. doi: 10.1124/dmd.110.035881. Epub 2010 Nov 12. Drug Metab Dispos. 2011. PMID: 21075975 Clinical Trial.
In vitro risk assessment of AZD9056 perpetrating a transporter-mediated drug-drug interaction with methotrexate.
Elsby R, Fox L, Stresser D, Layton M, Butters C, Sharma P, Smith V, Surry D. Elsby R, et al. Eur J Pharm Sci. 2011 May 18;43(1-2):41-9. doi: 10.1016/j.ejps.2011.03.006. Epub 2011 Apr 1. Eur J Pharm Sci. 2011. PMID: 21440623
Determination of the human cytochrome P450 isoforms involved in the metabolism of zolmitriptan.
Wild MJ, McKillop D, Butters CJ. Wild MJ, et al. Among authors: butters cj. Xenobiotica. 1999 Aug;29(8):847-57. doi: 10.1080/004982599238290. Xenobiotica. 1999. PMID: 10553725
Effects of propofol on human hepatic microsomal cytochrome P450 activities.
McKillop D, Wild MJ, Butters CJ, Simcock C. McKillop D, et al. Among authors: butters cj. Xenobiotica. 1998 Sep;28(9):845-53. doi: 10.1080/004982598239092. Xenobiotica. 1998. PMID: 9764927
Enzyme-inducing effects of bicalutamide in mouse, rat and dog.
McKillop D, Butters CJ, Hill SJ, Simons PJ, Edwards TL, Doughty SE. McKillop D, et al. Among authors: butters cj. Xenobiotica. 1998 May;28(5):465-78. doi: 10.1080/004982598239399. Xenobiotica. 1998. PMID: 9622849
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