Bykov VJ - Search Results

1

Novel cancer therapy by reactivation of the p53 apoptosis pathway.

Bykov VJ, Wiman KG. Bykov VJ, et al. Ann Med. 2003;35(7):458-65. doi: 10.1080/07853890310017152. Ann Med. 2003. PMID: 14649328 Review.

2

Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound.

Bykov VJ, Issaeva N, Shilov A, Hultcrantz M, Pugacheva E, Chumakov P, Bergman J, Wiman KG, Selivanova G. Bykov VJ, et al. Nat Med. 2002 Mar;8(3):282-8. doi: 10.1038/nm0302-282. Nat Med. 2002. PMID: 11875500

3

Characterization of the p53-rescue drug CP-31398 in vitro and in living cells.

Rippin TM, Bykov VJ, Freund SM, Selivanova G, Wiman KG, Fersht AR. Rippin TM, et al. Among authors: bykov vj. Oncogene. 2002 Mar 28;21(14):2119-29. doi: 10.1038/sj.onc.1205362. Oncogene. 2002. PMID: 11948395

4

Mutant p53-dependent growth suppression distinguishes PRIMA-1 from known anticancer drugs: a statistical analysis of information in the National Cancer Institute database.

Bykov VJ, Issaeva N, Selivanova G, Wiman KG. Bykov VJ, et al. Carcinogenesis. 2002 Dec;23(12):2011-8. doi: 10.1093/carcin/23.12.2011. Carcinogenesis. 2002. PMID: 12507923

5

Small molecules that reactivate mutant p53.

Bykov VJ, Selivanova G, Wiman KG. Bykov VJ, et al. Eur J Cancer. 2003 Sep;39(13):1828-34. doi: 10.1016/s0959-8049(03)00454-4. Eur J Cancer. 2003. PMID: 12932659 Review.

6

PRIMA-1(MET) synergizes with cisplatin to induce tumor cell apoptosis.

Bykov VJ, Zache N, Stridh H, Westman J, Bergman J, Selivanova G, Wiman KG. Bykov VJ, et al. Oncogene. 2005 May 12;24(21):3484-91. doi: 10.1038/sj.onc.1208419. Oncogene. 2005. PMID: 15735745

7

Reactivation of mutant p53 and induction of apoptosis in human tumor cells by maleimide analogs.

Bykov VJ, Issaeva N, Zache N, Shilov A, Hultcrantz M, Bergman J, Selivanova G, Wiman KG. Bykov VJ, et al. J Biol Chem. 2005 Aug 26;280(34):30384-91. doi: 10.1074/jbc.M501664200. Epub 2005 Jul 1. J Biol Chem. 2005. PMID: 15998635 Free article.

8

In vitro and in vivo cytotoxic effects of PRIMA-1 on hepatocellular carcinoma cells expressing mutant p53ser249.

Shi H, Lambert JM, Hautefeuille A, Bykov VJ, Wiman KG, Hainaut P, Caron de Fromentel C. Shi H, et al. Among authors: bykov vj. Carcinogenesis. 2008 Jul;29(7):1428-34. doi: 10.1093/carcin/bgm266. Epub 2007 Nov 28. Carcinogenesis. 2008. PMID: 18048389

9

PRIMA-1MET inhibits growth of mouse tumors carrying mutant p53.

Zache N, Lambert JM, Wiman KG, Bykov VJ. Zache N, et al. Among authors: bykov vj. Cell Oncol. 2008;30(5):411-8. doi: 10.3233/clo-2008-0440. Cell Oncol. 2008. PMID: 18791272 Free PMC article.

10

Mutant p53 targeting by the low molecular weight compound STIMA-1.

Zache N, Lambert JM, Rökaeus N, Shen J, Hainaut P, Bergman J, Wiman KG, Bykov VJ. Zache N, et al. Among authors: bykov vj. Mol Oncol. 2008 Jun;2(1):70-80. doi: 10.1016/j.molonc.2008.02.004. Epub 2008 Mar 7. Mol Oncol. 2008. PMID: 19383329 Free PMC article.

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