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Viral genome RNA degradation by sequence-selective, nucleic-acid hydrolyzing antibody inhibits the replication of influenza H9N2 virus without significant cytotoxicity to host cells.
Kim A, Lee JY, Byun SJ, Kwon MH, Kim YS. Kim A, et al. Among authors: byun sj. Antiviral Res. 2012 May;94(2):157-67. doi: 10.1016/j.antiviral.2012.03.007. Epub 2012 Mar 30. Antiviral Res. 2012. PMID: 22484663
A nucleic-acid hydrolyzing single chain antibody confers resistance to DNA virus infection in hela cells and C57BL/6 mice.
Lee G, Yu J, Cho S, Byun SJ, Kim DH, Lee TK, Kwon MH, Lee S. Lee G, et al. Among authors: byun sj. PLoS Pathog. 2014 Jun 26;10(6):e1004208. doi: 10.1371/journal.ppat.1004208. eCollection 2014 Jun. PLoS Pathog. 2014. PMID: 24968358 Free PMC article.
Development of Lactobacillus paracasei harboring nucleic acid-hydrolyzing 3D8 scFv as a preventive probiotic against murine norovirus infection.
Hoang PM, Cho S, Kim KE, Byun SJ, Lee TK, Lee S. Hoang PM, et al. Among authors: byun sj. Appl Microbiol Biotechnol. 2015 Mar;99(6):2793-803. doi: 10.1007/s00253-014-6257-7. Epub 2014 Dec 9. Appl Microbiol Biotechnol. 2015. PMID: 25487889
Profiling of viral proteins expressed from the genomic RNA of Japanese encephalitis virus using a panel of 15 region-specific polyclonal rabbit antisera: implications for viral gene expression.
Kim JK, Kim JM, Song BH, Yun SI, Yun GN, Byun SJ, Lee YM. Kim JK, et al. Among authors: byun sj. PLoS One. 2015 Apr 27;10(4):e0124318. doi: 10.1371/journal.pone.0124318. eCollection 2015. PLoS One. 2015. PMID: 25915765 Free PMC article.
Therapeutic Strategy for the Prevention of Pseudorabies Virus Infection in C57BL/6 Mice by 3D8 scFv with Intrinsic Nuclease Activity.
Lee G, Cho S, Hoang PM, Kim D, Lee Y, Kil EJ, Byun SJ, Lee TK, Kim DH, Kim S, Lee S. Lee G, et al. Among authors: byun sj. Mol Cells. 2015 Sep;38(9):773-80. doi: 10.14348/molcells.2015.0073. Epub 2015 Aug 7. Mol Cells. 2015. PMID: 26255831 Free PMC article.
Preventive Activity against Influenza (H1N1) Virus by Intranasally Delivered RNA-Hydrolyzing Antibody in Respiratory Epithelial Cells of Mice.
Cho S, Youn HN, Hoang PM, Cho S, Kim KE, Kil EJ, Lee G, Cho MJ, Hong J, Byun SJ, Song CS, Lee S. Cho S, et al. Among authors: byun sj. Viruses. 2015 Sep 21;7(9):5133-44. doi: 10.3390/v7092863. Viruses. 2015. PMID: 26402693 Free PMC article.
Functional stability of 3D8 scFv, a nucleic acid-hydrolyzing single chain antibody, under different biochemical and physical conditions.
Lee J, Park H, Kim M, Seo Y, Lee Y, Byun SJ, Lee S, Kwon MH. Lee J, et al. Among authors: byun sj. Int J Pharm. 2015 Dec 30;496(2):561-70. doi: 10.1016/j.ijpharm.2015.10.076. Epub 2015 Nov 1. Int J Pharm. 2015. PMID: 26536531
The catalytic activity of a recombinant single chain variable fragment nucleic acid-hydrolysing antibody varies with fusion tag and expression host.
Lee J, Kim M, Seo Y, Lee Y, Park H, Byun SJ, Kwon MH. Lee J, et al. Among authors: byun sj. Arch Biochem Biophys. 2017 Nov 1;633:110-117. doi: 10.1016/j.abb.2017.09.004. Epub 2017 Sep 6. Arch Biochem Biophys. 2017. PMID: 28888872
Heparan sulfate proteoglycans (HSPGs) and chondroitin sulfate proteoglycans (CSPGs) function as endocytic receptors for an internalizing anti-nucleic acid antibody.
Park H, Kim M, Kim HJ, Lee Y, Seo Y, Pham CD, Lee J, Byun SJ, Kwon MH. Park H, et al. Among authors: byun sj. Sci Rep. 2017 Oct 30;7(1):14373. doi: 10.1038/s41598-017-14793-z. Sci Rep. 2017. PMID: 29085061 Free PMC article.
Survival of Escherichia coli harboring nucleic acid-hydrolyzing 3D8 scFv during RNA virus infection.
Park JH, Lee JW, Choi H, Jung SK, Kim JS, Kim KW, Oh KB, Yang H, Byun SJ. Park JH, et al. Among authors: byun sj. Regul Toxicol Pharmacol. 2018 Apr;94:286-292. doi: 10.1016/j.yrtph.2018.02.012. Epub 2018 Feb 24. Regul Toxicol Pharmacol. 2018. PMID: 29486271 Free PMC article.
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