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Survivin expression is a negative prognostic marker in laryngeal squamous cell carcinoma and is associated with p53 accumulation.
Pizem J, Cör A, Gale N. Pizem J, et al. Histopathology. 2004 Aug;45(2):180-6. doi: 10.1111/j.1365-2559.2004.01925.x. Histopathology. 2004. PMID: 15279637
A high level of survivin expression and a supraglottic site of the tumour were two independent adverse prognostic factors in LSCC. CONCLUSIONS: Survivin is expressed in a varying proportion of cells in virtually all cases of LSCC. A high level of its e
A high level of survivin expression and a supraglottic site of the tumour were two independent adverse prognostic factors in L
Prognostic significance of apoptosis in medulloblastoma.
Pizem J, Cör A, Zadravec Zaletel L, Popovic M. Pizem J, et al. Neurosci Lett. 2005 Jun 10-17;381(1-2):69-73. doi: 10.1016/j.neulet.2005.02.021. Epub 2005 Feb 25. Neurosci Lett. 2005. PMID: 15882792
Since apoptosis is a major contributor to cell loss in medulloblastoma, either spontaneous or induced by radiation and chemotherapy, the apoptotic rate in resection specimens could have prognostic significance. We analysed the apoptotic rate in 58 medulloblastoma resection …
Since apoptosis is a major contributor to cell loss in medulloblastoma, either spontaneous or induced by radiation and chemotherapy, …
Immunohistochemical analysis of pro- and active-caspase 3 in laryngeal squamous cell carcinoma.
Cör A, Pizem J, Gale N. Cör A, et al. Virchows Arch. 2004 May;444(5):439-46. doi: 10.1007/s00428-004-0997-1. Epub 2004 Mar 25. Virchows Arch. 2004. PMID: 15045586
Our results suggest that the expression of pro-caspase 3, a key executioner caspase in apoptosis, is downregulated in a proportion of LSCC, but this is not associated with decreased apoptotic activity, measured by active-caspase 3 labelling....
Our results suggest that the expression of pro-caspase 3, a key executioner caspase in apoptosis, is downregulated in a propor …
Cyclooxygenase-2 expression determines neo-angiogenesis in gallbladder carcinomas.
Legan M, Luzar B, Ferlan-Marolt V, Cör A. Legan M, et al. Bosn J Basic Med Sci. 2006 Nov;6(4):58-63. doi: 10.17305/bjbms.2006.3122. Bosn J Basic Med Sci. 2006. PMID: 17177652 Free PMC article.
Mitotic count, brain invasion, and location are independent predictors of recurrence-free survival in primary atypical and malignant meningiomas: a study of 86 patients.
Vranic A, Popovic M, Cör A, Prestor B, Pizem J. Vranic A, et al. Neurosurgery. 2010 Oct;67(4):1124-32. doi: 10.1227/NEU.0b013e3181eb95b7. Neurosurgery. 2010. PMID: 20881577
Expression of Gli1 and PARP1 in medulloblastoma: an immunohistochemical study of 65 cases.
Pizem J, Popovic M, Cör A. Pizem J, et al. J Neurooncol. 2011 Jul;103(3):459-67. doi: 10.1007/s11060-010-0431-2. Epub 2010 Oct 16. J Neurooncol. 2011. PMID: 20953661
We analysed expression and localisation of Gli1, β-catenin and PARP1 by immunohistochemistry in a series of 65 consecutive medulloblastomas. ...It might be useful as a target to increase the effectiveness of current treatment modalities....
We analysed expression and localisation of Gli1, β-catenin and PARP1 by immunohistochemistry in a series of 65 consecutive medullobla …
Is survivin expression prognostic or predictive in malignant pleural mesothelioma?
Hmeljak J, Erčulj N, Dolžan V, Pižem J, Kern I, Kovač V, Cemažar M, Cör A. Hmeljak J, et al. Virchows Arch. 2013 Mar;462(3):315-21. doi: 10.1007/s00428-013-1373-9. Epub 2013 Jan 29. Virchows Arch. 2013. PMID: 23358691
Archival pleural mesothelioma tissue samples from 101 patients were immunohistochemically analysed for nuclear expression of survivin, for proliferation with the use of Ki-67 as marker and for apoptosis using active caspase-3 as a marker. Staining results and clinical data …
Archival pleural mesothelioma tissue samples from 101 patients were immunohistochemically analysed for nuclear expression of survivin, for p …
BIRC5 promoter SNPs do not affect nuclear survivin expression and survival of malignant pleural mesothelioma patients.
Hmeljak J, Erčulj N, Dolžan V, Kern I, Cör A. Hmeljak J, et al. J Cancer Res Clin Oncol. 2011 Nov;137(11):1641-51. doi: 10.1007/s00432-011-1030-0. Epub 2011 Aug 23. J Cancer Res Clin Oncol. 2011. PMID: 21861135
Apoptosis deregulation is an important feature of cancer and survivin, a member of the inhibitor-of-apoptosis-protein family encoded by the BIRC5 gene, has been suggested to have a role in the development and progression of several cancers. ...We observed that BIRC5 …
Apoptosis deregulation is an important feature of cancer and survivin, a member of the inhibitor-of-apoptosis-protein family encoded …
Microdissection techniques for cancer analysis.
Cör A, Vogt N, Malfoy B. Cör A, et al. Folia Biol (Praha). 2002;48(1):3-8. Folia Biol (Praha). 2002. PMID: 11871858 Review.
One difficulty in studying molecular changes of tumours has been the inability to isolate DNA and RNA from a homogeneous cell population. ...Microdissection is a technique for rapid and easy procurement of a pure cellular subpopulation away from its complex t …
One difficulty in studying molecular changes of tumours has been the inability to isolate DNA and RNA from a homogeneous cell populat …
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